The relationship between gray/white matter contrast and cognitive performance in first-episode schizophrenia

• Published in: Cerebral cortex (New York, N.Y. 1991) Vol. 34; no. 2
• Main Authors: Kobayashi, Haruko, Sasabayashi, Daiki, Takahashi, Tsutomu, Furuichi, Atsushi, Kido, Mikio, Takayanagi, Yoichiro, Noguchi, Kyo, Suzuki, Michio
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 31.01.2024
• Subjects: executive dysfunction; magnetic resonance imaging; schizophrenia; verbal learning deficits; intracortical myelin

Previous postmortem brain studies have revealed disturbed myelination in the intracortical regions in patients with schizophrenia, possibly reflecting anomalous brain maturational processes. However, it currently remains unclear whether this anomalous myelination is already present in early illness...