Protective immunity against HEV

• Published in: Current opinion in virology Vol. 5; pp. 1 - 6
• Main Authors: Huang, Shou-Jie, Liu, Xiao-Hui, Zhang, Jun, Ng, Mun-Hon
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2014
• Subjects: Animals; Hepatitis E - immunology; Hepatitis E - prevention & control; Hepatitis E - virology; Hepatitis E virus; Hepatitis E virus - genetics; Hepatitis E virus - immunology; Hepatitis E virus - physiology; Humans; Immunity, Innate

•The zoonotic genotype 4 hepatitis E virus is the most common cause of acute viral hepatitis in rural eastern China.•Infection is common, but virtually all are subclinical.•Naturally acquired immunity affords 75% protection against the infection.•However, protective immunity is extended to 38% of po...