Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD - Wang, Panpan; Fu, Tingting; Zhang, Xiaoyu; Yang, Fengyuan; Zheng, Guoxun; Xue, Weiwei; Chen, Yuzong; Yao, Xiaojun; Zhu, Feng (Biochimica et biophysica acta. General subjects, 2017)
Keywords: ADHD; aromatic compounds; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention Deficit Disorder with Hyperactivity - metabolism; Attention Deficit Disorder with Hyperactivity - pathology; Binding mode; Dopamine - chemistry; Dopamine - metabolism; Dopamine Antagonists - administration & dosage; Dopamine Antagonists - chemistry; Gibbs free energy; Humans; hydrophobicity; moieties; Molecular Docking Simulation; Molecular dynamics; Molecular Dynamics Simulation; molecular models; norepinephrine; Norepinephrine - antagonists & inhibitors; Norepinephrine - chemistry; Norepinephrine - metabolism; Norepinephrine-dopamine reuptake inhibitors; Selective norepinephrine reuptake inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors - administration & dosage; Serotonin and Noradrenaline Reuptake Inhibitors - chemistry; therapeutics; Molecular dynamics; Binding mode; ADHD; Norepinephrine-dopamine reuptake inhibitors; Selective norepinephrine reuptake inhibitors