Receptor-based targeting of engineered nanocarrier against solid tumors: Recent progress and challenges ahead

• Published in: Biochimica et biophysica acta. General subjects Vol. 1865; no. 2; p. 129777
• Main Authors: Akhter, Md. Habban, Beg, Sarwar, Tarique, Mohammed, Malik, Arshi, Afaq, Sarah, Choudhry, Hani, Hosawi, Salman
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2021
• Subjects: Animals; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - pharmacokinetics; Cancer; cancer therapy; Drug Carriers - chemistry; Drug Carriers - metabolism; Drug delivery; Drug Delivery Systems - methods; drugs; ErbB Receptors - metabolism; Humans; nanocarriers; nanomedicine; Nanomedicine - methods; Nanomedicines; neoplasms; Neoplasms - drug therapy; Neoplasms - metabolism; permeability; Receptor targeting; Theranostics; Tumor metastasis; Tumor Microenvironment - drug effects; Receptor targeting; Drug delivery; Theranostics; Nanomedicines; Cancer; Tumor metastasis

Background In past few decades, the research on engineered nanocarriers (NCs) has gained significant attention in cancer therapy due to selective delivery of drug molecules on the diseased cells thereby preventing unwanted uptake into healthy cells to cause toxicity. Scope of review The applicabilit...