Optical fiber tips for biological applications: From light confinement, biosensing to bioparticles manipulation

• Published in: Biochimica et biophysica acta. General subjects Vol. 1862; no. 5; pp. 1209 - 1246
• Main Authors: Paiva, Joana S., Jorge, Pedro A.S., Rosa, Carla C., Cunha, João P.S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2018
• Subjects: Animals; Biology; Biosensing Techniques - methods; Biosensing Techniques - trends; biosensors; Fiber optics; Humans; image analysis; light microscopy; Microfabrication; microparticles; Microscopy - methods; Microscopy - trends; nanoparticles; neurodegenerative diseases; Optical fiber sensors; Optical fiber tips; Optical fiber tweezers (OFTs); Optical Fibers; organelles; Protein Aggregates; spectroscopy; PVA/PAA; SECM-AFM; OPD; Optical fiber tweezers (OFTs); PCFs; AFM; Optical fiber tips; Biology; FP; s-SNOM; STM; Fiber optics; KPFM; SRM; PETIA; UNOM; SPM; OFTs; Microfabrication; DMD; FRET; NSTM; FIB; SNOM; MMF; pMBA; AFM–SNOM; BPENB; SMF; LOT; NPs; Optical fiber sensors; NA; PMMA; RI; SEM; TIR; TEM; HF
• ISSN: 0304-4165; 1872-8006
• DOI: 10.1016/j.bbagen.2018.02.008

The tip of an optical fiber has been considered an attractive platform in Biology. The simple cleaved end of an optical fiber can be machined, patterned and/or functionalized, acquiring unique properties enabling the exploitation of novel optical phenomena. Prompted by the constant need to measure a...