Post-translational regulation and modifications of flavivirus structural proteins

• Published in: Journal of general virology Vol. 96; no. Pt 7; pp. 1551 - 1569
• Main Authors: Roby, Justin A, Setoh, Yin Xiang, Hall, Roy A, Khromykh, Alexander A
• Format: Journal Article
• Language: English
• Published: England 01.07.2015
• Subjects: Capsid Proteins - metabolism; Flavivirus - physiology; Gene Expression Regulation, Viral; Glycosylation; Host-Pathogen Interactions; Humans; Protein Multimerization; Protein Processing, Post-Translational; Proteolysis; Viral Envelope Proteins - metabolism; Virus Assembly; Virus Release

Flaviviruses are a group of single-stranded, positive-sense RNA viruses that generally circulate between arthropod vectors and susceptible vertebrate hosts, producing significant human and veterinary disease burdens. Intensive research efforts have broadened our scientific understanding of the repli...