HMG-CoA Reductase Inhibitors Decrease CD11b Expression and CD11b-Dependent Adhesion of Monocytes to Endothelium and Reduce Increased Adhesiveness of Monocytes Isolated From Patients With Hypercholesterolemia - Weber, Christian; Erl, Wolfgang; Weber, Kim S.C; Weber, Peter C (Journal of the American College of Cardiology, 1997)
Keywords: Cell Adhesion - drug effects; Cells, Cultured; Endothelium, Vascular - cytology; Endothelium, Vascular - drug effects; Fluorescent Antibody Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Hypercholesterolemia - blood; Hypercholesterolemia - drug therapy; Lovastatin - pharmacology; Lovastatin - therapeutic use; Macrophage-1 Antigen - metabolism; Male; Monocytes - drug effects; Monocytes - metabolism; Simvastatin - pharmacology; Simvastatin - therapeutic use; HDL; GTP; MCP-1; LDL; HMG-CoA; ICAM-1; PBMCs; CHD; HUVECs; mAb