Phase III Randomized Trial of Calendula Officinalis Compared With Trolamine for the Prevention of Acute Dermatitis During Irradiation for Breast Cancer

• Published in: Journal of clinical oncology Vol. 22; no. 8; pp. 1447 - 1453
• Main Authors: POMMIER, P, GOMEZ, F, SUNYACH, M. P, D'HOMBRES, A, CARRIE, C, MONTBARBON, X
• Format: Journal Article
• Language: English
• Published: Baltimore, MD American Society of Clinical Oncology 15.04.2004; Lippincott Williams & Wilkins
• Subjects: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Biological and medical sciences; Breast Neoplasms - radiotherapy; Calendula; Combined Modality Therapy; Dermatology; Ethanolamines - therapeutic use; Female; Humans; Medical sciences; Middle Aged; Ointments - therapeutic use; Plant Extracts - administration & dosage; Plant Extracts - therapeutic use; Radiation Injuries; Radiodermatitis - prevention & control; Radiotherapy, Adjuvant; Skin involvement in other diseases. Miscellaneous. General aspects; Phase III trial; Prevention; Skin disease; Randomization; Acute; Irradiation; Trolamine; Breast cancer; Mammary gland; Malignant tumor; Dermatitis; Comparative study

The effectiveness of nonsteroid topical agents for the prevention of acute dermatitis during adjuvant radiotherapy for breast carcinoma has not been demonstrated. The goal of this study was to compare the effectiveness of calendula (Pommade au Calendula par Digestion; Boiron Ltd, Levallois-Perret, F...