Efficacy of the Fractional Photothermolysis System with Dynamic Operating Mode on Acne Scars and Enlarged Facial Pores
BACKGROUND Current treatments for acne scars and enlarged facial pores have shown limited efficacy. OBJECTIVE To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores. MATERIALS AND METHODS Twelve patients with m...
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Published in | Dermatologic surgery Vol. 35; no. 1; pp. 108 - 114 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Malden, USA
Blackwell Publishing Inc
01.01.2009
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Abstract | BACKGROUND
Current treatments for acne scars and enlarged facial pores have shown limited efficacy.
OBJECTIVE
To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores.
MATERIALS AND METHODS
Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar– and facial pore–treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores.
RESULTS
Follow‐up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post‐treatment erythema, and edema, were resolved within 1 week.
CONCLUSION
We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo‐controlled, split‐face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode. |
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AbstractList | BACKGROUND
Current treatments for acne scars and enlarged facial pores have shown limited efficacy.
OBJECTIVE
To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores.
MATERIALS AND METHODS
Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar– and facial pore–treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores.
RESULTS
Follow‐up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post‐treatment erythema, and edema, were resolved within 1 week.
CONCLUSION
We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo‐controlled, split‐face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode. BACKGROUNDCurrent treatments for acne scars and enlarged facial pores have shown limited efficacy.OBJECTIVETo evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores.MATERIALS AND METHODSTwelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar- and facial pore-treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores.RESULTSFollow-up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post-treatment erythema, and edema, were resolved within 1 week.CONCLUSIONWe suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo-controlled, split-face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode. |
Author | LEE, JU HEE LEE, KYU‐YEOP OH, SANG HO CHO, SUNG BIN CHOI, MOON JUNG |
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References | 2004; 30 2005; 210 2000; 26 2006; 32 2000; 13 2006; 38 1999; 38 2004; 34 1999; 25 2004; 6 2003; 16 2003; 5 2002; 138 2005; 17 2007; 33 2007; 13 2006; 155 Jo (10.1111/j.1524-4725.2008.34399.x-BIB8) 2007; 13 Abraham (10.1111/j.1524-4725.2008.34399.x-BIB14) 2004; 6 Tanzi (10.1111/j.1524-4725.2008.34399.x-BIB9) 2004; 30 Brazil (10.1111/j.1524-4725.2008.34399.x-BIB11) 2003; 5 Uhoda (10.1111/j.1524-4725.2008.34399.x-BIB10) 2005; 210 Piérard (10.1111/j.1524-4725.2008.34399.x-BIB5) 2003; 16 Hernandez-Perez (10.1111/j.1524-4725.2008.34399.x-BIB15) 2000; 26 Piérard (10.1111/j.1524-4725.2008.34399.x-BIB6) 2000; 13 Phillips (10.1111/j.1524-4725.2008.34399.x-BIB13) 2002; 138 Geronemus (10.1111/j.1524-4725.2008.34399.x-BIB20) 2006; 38 Tse (10.1111/j.1524-4725.2008.34399.x-BIB3) 2005; 17 Behroozan (10.1111/j.1524-4725.2008.34399.x-BIB4) 2006; 32 Manstein (10.1111/j.1524-4725.2008.34399.x-BIB18) 2004; 34 Bitter (10.1111/j.1524-4725.2008.34399.x-BIB12) 2000; 26 Roh (10.1111/j.1524-4725.2008.34399.x-BIB7) 2006; 155 Laubach (10.1111/j.1524-4725.2008.34399.x-BIB19) 2006; 38 Schmidt (10.1111/j.1524-4725.2008.34399.x-BIB16) 1999; 38 Grimes (10.1111/j.1524-4725.2008.34399.x-BIB17) 1999; 25 Kim (10.1111/j.1524-4725.2008.34399.x-BIB1) 2005; 17 Glaich (10.1111/j.1524-4725.2008.34399.x-BIB2) 2007; 33 |
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laser contributor: fullname: Tse – volume: 17 start-page: 93 year: 2005 ident: 10.1111/j.1524-4725.2008.34399.x-BIB1 article-title: Treatment of acneiform scars with fractional photothermolysis contributor: fullname: Kim – volume: 38 start-page: 142 year: 2006 ident: 10.1111/j.1524-4725.2008.34399.x-BIB19 article-title: Skin responses to fractional photothermolysis contributor: fullname: Laubach – volume: 13 start-page: 372 year: 2000 ident: 10.1111/j.1524-4725.2008.34399.x-BIB6 article-title: EEMCO guidance for the in vivo assessment of skin greasiness contributor: fullname: Piérard – volume: 6 start-page: 136 year: 2004 ident: 10.1111/j.1524-4725.2008.34399.x-BIB14 article-title: Clinical evaluation of nonablative radiofrequency facial rejuvenation contributor: fullname: Abraham – volume: 26 start-page: 649 year: 2000 ident: 10.1111/j.1524-4725.2008.34399.x-BIB15 article-title: Oral isotretinoin as part of the treatment of cutaneous aging contributor: fullname: Hernandez-Perez – volume: 38 start-page: 149 year: 1999 ident: 10.1111/j.1524-4725.2008.34399.x-BIB16 article-title: Tretinoin-iontophoresis in atrophic acne scars contributor: fullname: Schmidt – volume: 138 start-page: 1486 year: 2002 ident: 10.1111/j.1524-4725.2008.34399.x-BIB13 article-title: Efficacy of 0.1% tazarotene cream for the treatment of photodamage contributor: fullname: Phillips – volume: 32 start-page: 298 year: 2006 ident: 10.1111/j.1524-4725.2008.34399.x-BIB4 article-title: Fractional photothermolysis for treatment of poikiloderma of Civatte contributor: fullname: Behroozan – volume: 5 start-page: 168 year: 2003 ident: 10.1111/j.1524-4725.2008.34399.x-BIB11 article-title: Long-term clinical results of IPL photorejuvenation contributor: fullname: Brazil – volume: 16 start-page: 324 year: 2003 ident: 10.1111/j.1524-4725.2008.34399.x-BIB5 article-title: EEMCO guidance for the efficacy assessment of antiperspirants and deodorants contributor: fullname: Piérard – volume: 25 start-page: 18 year: 1999 ident: 10.1111/j.1524-4725.2008.34399.x-BIB17 article-title: The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups contributor: fullname: Grimes – volume: 38 start-page: 169 year: 2006 ident: 10.1111/j.1524-4725.2008.34399.x-BIB20 article-title: Fractional photothermolysis contributor: fullname: Geronemus – volume: 13 start-page: 162 year: 2007 ident: 10.1111/j.1524-4725.2008.34399.x-BIB8 article-title: Quantitative research on skin pore widening using a stereoimage optical topometer and Sebutape contributor: fullname: Jo – volume: 33 start-page: 289 year: 2007 ident: 10.1111/j.1524-4725.2008.34399.x-BIB2 article-title: Fractional resurfacing for the treatment of hypopigmented scars contributor: fullname: Glaich – volume: 26 start-page: 835 year: 2000 ident: 10.1111/j.1524-4725.2008.34399.x-BIB12 article-title: Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments contributor: fullname: Bitter – volume: 210 start-page: 3 year: 2005 ident: 10.1111/j.1524-4725.2008.34399.x-BIB10 article-title: The conundrum of skin pores in dermocosmetology contributor: fullname: Uhoda – volume: 30 start-page: 152 year: 2004 ident: 10.1111/j.1524-4725.2008.34399.x-BIB9 article-title: Comparison of a 1450-nm diode laser and a 1320-nm Nd:YAG laser in the treatment of atrophic facial scars contributor: fullname: Tanzi |
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Snippet | BACKGROUND
Current treatments for acne scars and enlarged facial pores have shown limited efficacy.
OBJECTIVE
To evaluate the efficacy and safety of the... BACKGROUNDCurrent treatments for acne scars and enlarged facial pores have shown limited efficacy.OBJECTIVETo evaluate the efficacy and safety of the... |
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Title | Efficacy of the Fractional Photothermolysis System with Dynamic Operating Mode on Acne Scars and Enlarged Facial Pores |
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