Chronic bilateral otomycosis caused by Aspergillus niger
Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloure...
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Published in | Mycoses Vol. 47; no. 1‐2; pp. 82 - 84 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Berling, Germany
Blackwell Verlag, GmbH
01.02.2004
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Subjects | |
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Abstract | Summary
Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi.
Zusammenfassung
Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen. |
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AbstractList | Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid-Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that 'Narayan' stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Zusammenfassung Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen. Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid-Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that 'Narayan' stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi.Original Abstract: Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46-jaehrigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau-schwarzer Massen in beiden Gehoergaengen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus-Konidiophoren in KOH-Praeparaten, Giemsa-Faerbung und Gram-Faerbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H & E- und PAS-Faerbung gesehen werden. Der Prozess heilte unter der Gabe von 1%-Mercurochrom- Loesung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungslaendern wie Indien empfohlen. Die Narayan-Faerbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen. Summary Aspergillus niger , an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Zusammenfassung Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus ‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen. |
Author | Mehta, Niral Mishra, G. S. Pal, M. |
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References | 1993; 26 1988; 67 1996 2001; 71 1982 1985; 99 2001; 78 1983; 77 1989 e_1_2_6_3_2 Pal M. (e_1_2_6_7_2) 2001; 71 Pal M (e_1_2_6_8_2) 2001; 78 Lucente FE. (e_1_2_6_5_2) 1993; 26 Stern JC (e_1_2_6_4_2) 1988; 67 e_1_2_6_10_2 Smith JMB. (e_1_2_6_9_2) 1989 Pahwa VK (e_1_2_6_2_2) 1983; 77 Chander J. (e_1_2_6_6_2) 1996 |
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Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who... Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was... Summary Aspergillus niger , an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient... |
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SubjectTerms | Anti-Infective Agents, Local - pharmacology Anti-Infective Agents, Local - therapeutic use Aspergillosis - drug therapy Aspergillosis - microbiology Aspergillosis - pathology Aspergillus niger Aspergillus niger - cytology Aspergillus niger - drug effects Aspergillus niger - isolation & purification Cerumen - microbiology Chronic Disease Earache Erythema Female Humans Hyphae - cytology Merbromin - pharmacology Merbromin - therapeutic use Middle Aged Otitis Externa - drug therapy Otitis Externa - microbiology Otitis Externa - pathology otomycosis Otomykose Pruritus |
Title | Chronic bilateral otomycosis caused by Aspergillus niger |
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