Chronic bilateral otomycosis caused by Aspergillus niger

Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloure...

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Published inMycoses Vol. 47; no. 1‐2; pp. 82 - 84
Main Authors Mishra, G. S., Mehta, Niral, Pal, M.
Format Journal Article
LanguageEnglish
Published Berling, Germany Blackwell Verlag, GmbH 01.02.2004
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Abstract Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Zusammenfassung Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen.
AbstractList Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid-Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that 'Narayan' stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi.
Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Zusammenfassung Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen.
Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid-Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that 'Narayan' stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi.Original Abstract: Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46-jaehrigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau-schwarzer Massen in beiden Gehoergaengen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus-Konidiophoren in KOH-Praeparaten, Giemsa-Faerbung und Gram-Faerbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H & E- und PAS-Faerbung gesehen werden. Der Prozess heilte unter der Gabe von 1%-Mercurochrom- Loesung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungslaendern wie Indien empfohlen. Die Narayan-Faerbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen.
Summary Aspergillus niger , an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who was unresponsive to different drugs. The patient showed signs of erythema, otalgia, itching, otorrhoea and presence of greyish black coloured mass in both the ear canals. The direct microscopical examination of the ear debris in potassium hydroxide preparations, Giemsa, phase contrast and Gram revealed many thin, branched septate hyphae, condia and conidiophores morphologically indistinguishable from Aspergillus spp. The histopathological section of the ear wax mass by haematoxylin and eosin and periodic acid‐Schiff techniques also showed similar fungal elements. The patient responded to 1% solution of mercurochrome. The use of mercurochrome in developing countries like India may be recommended to treat the fungal otitis in patients. We also emphasize that ‘Narayan’ stain should be routinely employed by microbiology and public health laboratories to study the morphology of pathogenic fungi. Zusammenfassung Aspergillus niger wurde als Erreger einer chronischen, bilateralen Otomykose bei einer 46‐jährigen Frau identifiziert bei bisher erfolgloser Behandlung mit mehreren Medikamenten. Die Symptome waren Erythem, Otalgie, Juckreiz, Otorrhoe und Vorhandensein grau‐schwarzer Massen in beiden Gehörgängen. Direktmikrospisch wurden reichlich verzweigte, septierte Hyphen, Konidiosporen und Aspergillus ‐Konidiophoren in KOH‐Präparaten, Giemsa‐Färbung und Gram‐Färbung gesehen. Diese Pilzelemente konnten auch histopathologisch im Ohrschmalz bei H&E‐ und PAS‐Färbung gesehen werden. Der Prozess heilte unter der Gabe von 1%‐Mercurochrom‐ Lösung ab. Mercurochrom wird als preiswertes Mittel zur Behandlung pilzbedingter Otitis in Entwicklungsländern wie Indien empfohlen. Die Narayan‐Färbung (Glycerin, Methylenblau, DMSO) zum Pilznachweis wird empfohlen.
Author Mehta, Niral
Mishra, G. S.
Pal, M.
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Cites_doi 10.1016/S0030-6665(20)30741-6
10.1017/S002221510009678X
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Snippet Summary Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient who...
Aspergillus niger, an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46-year-old female patient who was...
Summary Aspergillus niger , an opportunistic filamentous fungus, was identified as the cause of chronic bilateral otomycosis in a 46‐year‐old female patient...
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SubjectTerms Anti-Infective Agents, Local - pharmacology
Anti-Infective Agents, Local - therapeutic use
Aspergillosis - drug therapy
Aspergillosis - microbiology
Aspergillosis - pathology
Aspergillus niger
Aspergillus niger - cytology
Aspergillus niger - drug effects
Aspergillus niger - isolation & purification
Cerumen - microbiology
Chronic Disease
Earache
Erythema
Female
Humans
Hyphae - cytology
Merbromin - pharmacology
Merbromin - therapeutic use
Middle Aged
Otitis Externa - drug therapy
Otitis Externa - microbiology
Otitis Externa - pathology
otomycosis
Otomykose
Pruritus
Title Chronic bilateral otomycosis caused by Aspergillus niger
URI https://onlinelibrary.wiley.com/doi/abs/10.1046%2Fj.0933-7407.2003.00935.x
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