Effect of Ovariohysterectomy at the Time of Tumor Removal in Dogs with Benign Mammary Tumors and Hyperplastic Lesions: A Randomized Controlled Clinical Trial

• Published in: Journal of veterinary internal medicine Vol. 27; no. 4; pp. 935 - 942
• Main Authors: Kristiansen, V.M., Nødtvedt, A., Breen, A.M., Langeland, M., Teige, J., Goldschmidt, M., Jonasdottir, T.J., Grotmol, T., Sørenmo, K.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2013; John Wiley & Sons, Inc
• Subjects: Animals; Breast cancer; Breast diseases; Cancer; Canine; Dog Diseases - surgery; Dogs; Female; Hyperplasia - pathology; Hyperplasia - veterinary; Hysterectomy - veterinary; Mammary Glands, Animal - pathology; Mammary Neoplasms, Animal - pathology; Medical prognosis; Multivariate Analysis; Nonmalignant mammary tumors; Ovariectomy - veterinary; Spaying; Steroids; Tumors; Spaying; Nonmalignant mammary tumors; Cancer; Canine

Background Nonmalignant mammary tumors (NMT) are common in intact female dogs. Little is known about the clinical significance of these tumors, and the effect of ovariohysterectomy (OHE) on their development. Hypothesis Ovarian hormone ablation through OHE decreases the risk of new tumors and thereb...