Nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase

• Published in: Microbiology (Society for General Microbiology) Vol. 140; no. 8; pp. 1817 - 1828
• Main Authors: Eikmanns, Bernhard J, Thum-Schmitz, Natalie, Eggeling, Lothar, Ludtke, Kai-Ulf, Sahm, Hermann
• Format: Journal Article
• Language: English
• Published: Reading Soc General Microbiol 01.08.1994; Society for General Microbiology
• Subjects: Amino Acid Sequence; Bacterial Proteins - antagonists & inhibitors; Bacterial Proteins - biosynthesis; Bacterial Proteins - genetics; Bacteriology; Base Sequence; Biological and medical sciences; Citrate (si)-Synthase - antagonists & inhibitors; Citrate (si)-Synthase - biosynthesis; Citrate (si)-Synthase - genetics; Cloning, Molecular; Corynebacterium - enzymology; Corynebacterium - genetics; Corynebacterium glutamicum; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetics; Microbiology; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins - biosynthesis; RNA, Bacterial - genetics; RNA, Messenger - genetics; Sequence Alignment; Sequence Homology, Amino Acid; Transcription, Genetic; Nucleotide sequence; Transcription; Enzyme; Lyases; Gene expression; Oxo-acid-lyases; Carbon-carbon lyases; Regulation(control); Enzymatic activity; Citrate (si)-synthase; Corynebacterium glutamicum; Bacteria; Actinomycetes; Corynebacteriaceae; Aminoacid sequence

Institut für Biotechnologie, 1 des Forschungszentrums Jülich, D-52425 Jülich, Germany ABSTRACT Citrate synthase catalyses the initial reaction of the citric acid cycle and can therefore be considered as the rate-controlling enzyme for the entry of substrates into the cycle. In Corynebacterium glutam...