Indocyanine-green-embedded PEBBLEs as a contrast agent for photoacoustic imaging

• Published in: Journal of biomedical optics Vol. 12; no. 4; p. 044020
• Main Authors: Kim, Gwangseong, Huang, Sheng-Wen, Day, Kathleen C, O'Donnell, Matthew, Agayan, Rodney R, Day, Mark A, Kopelman, Raoul, Ashkenazi, Shai
• Format: Journal Article
• Language: English
• Published: United States 01.07.2007
• Subjects: Cell Line, Tumor; Contrast Media; Drug Carriers - chemistry; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Indocyanine Green; Lasers; Nanoparticles - chemistry; Neoplasms - pathology; Ultrasonography - methods

Nanoparticles 100 nm in diameter containing indocyanine green (ICG) have been developed as a contrast agent for photoacoustic (PA) imaging based on (photonic explorers for biomedical use by biologically localized embedding PEBBLE) technology using organically modified silicate (ormosil) as a matrix....