Vascular Endothelial Growth Factor in Porcine Coronary Arteries Following Balloon Angioplasty

• Published in: Journal of investigative surgery Vol. 12; no. 1; pp. 15 - 23
• Main Authors: Hausner, E A, Orsini, J A, Foster, L L, Modzelewski, T C, Merrill, J J, Perkowski, S Z, Slee, A
• Format: Journal Article
• Language: English
• Published: United States Informa UK Ltd 1999; Taylor & Francis
• Subjects: Angioplasty, Balloon, Coronary; Animals; Arteriosclerosis - chemically induced; Arteriosclerosis - therapy; Cholesterol - blood; Cholesterol, Dietary; Coronary Vessels - cytology; Coronary Vessels - pathology; Coronary Vessels - physiology; Dietary Fats; Endothelial Growth Factors - analysis; Endothelial Growth Factors - metabolism; Lymphokines - analysis; Lymphokines - metabolism; Neovascularization, Physiologic; Porcine Angioplasty Growth Factors; Proliferating Cell Nuclear Antigen - analysis; Swine; Tunica Intima - cytology; Tunica Intima - pathology; Tunica Intima - physiology; Tunica Media - cytology; Tunica Media - pathology; Tunica Media - physiology; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wound Healing

The present study was a preliminary inquiry into the presence of vascular endothelial growth factor (VEGF)in a model of coronary artery response to injury. We examined domestic pigs who had received a diet enriched in saturated fat and cholesterol and undergone balloon angioplasty of one or more cor...