The expression of microRNAs and exposure to environmental contaminants related to human health: a review

• Published in: International journal of environmental health research Vol. 32; no. 2; pp. 332 - 354
• Main Authors: Tumolo, Maria Rosaria, Panico, Alessandra, De Donno, Antonella, Mincarone, Pierpaolo, Leo, Carlo Giacomo, Guarino, Roberto, Bagordo, Francesco, Serio, Francesca, Idolo, Adele, Grassi, Tiziana, Sabina, Saverio
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.02.2022; Taylor & Francis LLC
• Subjects: 1-Phosphatidylinositol 3-kinase; Abbreviations; Adhesion; Air pollution; AKT protein; Antigens; Apoptosis; Apoptosis Regulatory Proteins; Aromatic compounds; Arsenic; B-cell lymphoma; Bcl-6 protein; Biological effects; Bisphenol A; Cardiovascular diseases; CD40 antigen; Cell adhesion; Cell adhesion molecules; Cell death; Cell surface; Chemokines; Chromium; Contaminants; Cyclin-dependent kinase; Cyclin-dependent kinases; Cytokines; Diesel engines; DNA-Binding Proteins; Environmental health; Environmental impact; environmental pollutants; Enzyme inhibitors; Gene expression; Growth factors; health; Heavy metals; Hemoglobin; Homology; Humans; Hydrocarbons; Interferon; Interleukin 1; Interleukin 6; Intracellular Signaling Peptides and Proteins; Kinases; Lead; Leukocytes; Lymphocytes B; Lymphoma; Mercury; MicroRNAs; MicroRNAs - genetics; Nitric oxide; Organic chemicals; Organic chemistry; Organophosphorus Compounds; Organophosphorus pesticides; Particulate matter; pathway; PCB; Pesticides; Phosphatidylinositol 3-Kinases - metabolism; Polychlorinated biphenyls; Polycyclic aromatic hydrocarbons; Proteins; RNA-Binding Proteins; Transcription factors; Transducers; Transforming growth factor-b; Tumor necrosis factor-TNF; Tumors; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A; Zinc; Zinc finger proteins; health; pathway; environmental pollutants; MicroRNAs

Environmental contaminants exposure may lead to detrimental changes to the microRNAs (miRNAs) expression resulting in several health effects. miRNAs, small non-coding RNAs that regulate gene expression, have multiple transcript targets and thereby regulate several signalling molecules. Even a minor...