Generation of data on within-subject biological variation in laboratory medicine: An update

• Published in: Critical reviews in clinical laboratory sciences Vol. 53; no. 5; pp. 313 - 325
• Main Authors: Braga, Federica, Panteghini, Mauro
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.10.2016; Taylor & Francis Ltd
• Subjects: analytical goals; between-subject biological variation; Biological variation; Biological Variation, Population; Data analysis; Diagnostic Techniques and Procedures - standards; Humans; index of individuality; inter-individual biological variation; Intra-individual biological variation; normality test; reference change value; Reference Values; Reproducibility of Results; within-subject biological variation; analytical goals; between-subject biological variation; normality test; reference change value; index of individuality; inter-individual biological variation; within-subject biological variation; Intra-individual biological variation

In recent decades, the study of biological variation of laboratory analytes has received increased attention. The reasons for this interest are related to the potential practical applications of such knowledge. Biological variation data allow the derivation of important parameters for the interpreta...