Bioactive compounds from Cudrania tricuspidata: A natural anticancer source

The tumor is becoming a critical threat to our lives in these years. Searching for antitumor substances from natural products is a great interest of scientists. Cudrania tricuspidata (C. tricuspidata) is a regional plant containing 158 flavonoids and 99 xanthones, and others ingredients with favorab...

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Published inCritical reviews in food science and nutrition Vol. 60; no. 3; pp. 494 - 514
Main Authors Li, Xusheng, Yao, Zilan, Jiang, Xinwei, Sun, Jianxia, Ran, Guojing, Yang, Xuan, Zhao, Yaqi, Yan, Ying, Chen, Zisheng, Tian, Lingmin, Bai, Weibin
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 04.02.2020
Taylor & Francis Ltd
Subjects
Anticancer properties
Antineoplastic Agents - chemistry
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
antitumor
Antitumor activity
Antitumor agents
Bioactive compounds
Biological activity
cancer
Cell viability
constituent
Cudrania tricuspidata
Flavonoids
Flavonoids - isolation & purification
Flavonoids - pharmacology
Fruit - chemistry
Humans
Isoflavones
Molecular modelling
Moraceae - chemistry
Natural products
Plant Extracts - chemistry
Plant Extracts - pharmacology
Sustainability
Tumors
Viability
xanthones
Xanthones - isolation & purification
Xanthones - pharmacology
cancer
Cudrania tricuspidata
flavonoids
antitumor
constituent
xanthones
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Abstract The tumor is becoming a critical threat to our lives in these years. Searching for antitumor substances from natural products is a great interest of scientists. Cudrania tricuspidata (C. tricuspidata) is a regional plant containing 158 flavonoids and 99 xanthones, and others ingredients with favorable bioactivity. This review comprehensively analyzes the antitumor compounds from C. tricuspidata against different tumors, and 78 flavonoids plus xanthones are considered as underlying antineoplastic. Importantly, the structure of preylation groups is the primary source of antitumor activity among 45 flavonoids plus xanthones, which could be a direction of structural modification for a better antitumor ability. Additionally, the fruits are also preferable sources of antitumor compounds compared to the roots and barks due to the abundant isoflavones and sustainability. However, many studies only focused on the cells viability inhibition of the compounds, the underlying molecular mechanisms, and the intracellular targets remain ambiguous. In conclusion, C. tricuspidata has a great potential for anti-tumor prevention or therapy, but more attention should be paid to deeper research in vitro and in vivo models.
AbstractList The tumor is becoming a critical threat to our lives in these years. Searching for antitumor substances from natural products is a great interest of scientists. Cudrania tricuspidata (C. tricuspidata) is a regional plant containing 158 flavonoids and 99 xanthones, and others ingredients with favorable bioactivity. This review comprehensively analyzes the antitumor compounds from C. tricuspidata against different tumors, and 78 flavonoids plus xanthones are considered as underlying antineoplastic. Importantly, the structure of preylation groups is the primary source of antitumor activity among 45 flavonoids plus xanthones, which could be a direction of structural modification for a better antitumor ability. Additionally, the fruits are also preferable sources of antitumor compounds compared to the roots and barks due to the abundant isoflavones and sustainability. However, many studies only focused on the cells viability inhibition of the compounds, the underlying molecular mechanisms, and the intracellular targets remain ambiguous. In conclusion, C. tricuspidata has a great potential for anti-tumor prevention or therapy, but more attention should be paid to deeper research in vitro and in vivo models.
The tumor is becoming a critical threat to our lives in these years. Searching for antitumor substances from natural products is a great interest of scientists. ( . ) is a regional plant containing 158 flavonoids and 99 xanthones, and others ingredients with favorable bioactivity. This review comprehensively analyzes the antitumor compounds from against different tumors, and 78 flavonoids plus xanthones are considered as underlying antineoplastic. Importantly, the structure of preylation groups is the primary source of antitumor activity among 45 flavonoids plus xanthones, which could be a direction of structural modification for a better antitumor ability. Additionally, the fruits are also preferable sources of antitumor compounds compared to the roots and barks due to the abundant isoflavones and sustainability. However, many studies only focused on the cells viability inhibition of the compounds, the underlying molecular mechanisms, and the intracellular targets remain ambiguous. In conclusion, . has a great potential for anti-tumor prevention or therapy, but more attention should be paid to deeper research and models.
Author Jiang, Xinwei
Chen, Zisheng
Ran, Guojing
Yao, Zilan
Yang, Xuan
Li, Xusheng
Zhao, Yaqi
Bai, Weibin
Tian, Lingmin
Sun, Jianxia
Yan, Ying
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  fullname: Yang, Xuan
  organization: Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University
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  givenname: Yaqi
  surname: Zhao
  fullname: Zhao, Yaqi
  organization: Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University
– sequence: 8
  givenname: Ying
  surname: Yan
  fullname: Yan, Ying
  organization: Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University
– sequence: 9
  givenname: Zisheng
  surname: Chen
  fullname: Chen, Zisheng
  organization: Department of Respiratory Medicine, The Sixth Affiliated Hospital of Guangzhou Medical University
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  givenname: Lingmin
  surname: Tian
  fullname: Tian, Lingmin
  organization: Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University
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  givenname: Weibin
  surname: Bai
  fullname: Bai, Weibin
  email: baiweibin@163.com
  organization: Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30582344$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1016/j.phymed.2015.07.006
10.1016/j.fitote.2015.02.011
10.1007/s11064-013-1119-8
10.1021/np4009333
10.1055/s-0033-1350619
10.1097/00008469-200106000-00007
10.1021/np068054v
10.3390/nu3100877
10.1016/j.fct.2017.12.007
10.1016/j.foodchem.2011.03.073
10.1016/j.eujim.2011.09.007
10.1271/bbb.64.1038
10.1021/cc0498231
10.1080/10408398.2016.1252711
10.1080/10519990802240387
10.1002/ardp.201200440
10.1248/bpb.b15-00835
10.1002/ijc.25119
10.3390/molecules22122130
10.1002/cbdv.200490164
10.4314/tjpr.v16i11.27
10.1002/ptr.2286
10.3184/174751913X13647406965542
10.1016/j.phytol.2012.05.010
10.1021/acs.jnatprod.6b00204
10.1155/2014/934691
10.1016/j.nut.2016.03.020
10.1021/cr900019j
10.1016/j.semcancer.2017.08.005
10.1016/j.phymed.2013.08.018
10.3390/molecules17067284
10.1038/sj.onc.1209162
10.1056/NEJMoa074306
10.6023/cjoc201406018
10.1016/j.phytochem.2004.04.025
10.1021/jf202898g
10.1016/j.cbi.2014.09.022
10.1016/j.jcat.2003.09.012
10.1016/j.ejmech.2010.06.025
10.1097/CAD.0000000000000044
10.1080/14786410701371041
10.3329/bjp.v11i2.25549
10.1016/j.ctrv.2009.11.007
10.1177/1934578X1200701119
10.3727/096504005776404562
10.1007/s11010-017-3111-0
10.3109/08820139.2010.516049
10.1016/j.lfs.2006.12.031
10.1016/j.fct.2017.06.009
10.11620/IJOB.2016.41.3.105
10.14715/cmb/2018.64.1.11
10.1093/annonc/mdi110
10.1248/bpb.b15-00767
10.1016/j.biopha.2017.08.048
10.1016/j.biopha.2014.11.016
10.3329/bjp.v8i3.14795
10.4314/tjpr.v14i4.8
10.1016/j.intimp.2008.11.008
10.1016/j.phymed.2016.04.007
10.1007/s12272-009-1118-0
10.18632/oncotarget.15264
10.1016/j.lfs.2015.10.004
10.1007/BF02114762
10.1007/s12272-016-0761-5
10.1016/j.fct.2017.08.007
10.1016/j.critrevonc.2017.09.004
10.2174/1381612822666160530150936
10.1186/s12935-014-0124-6
10.1016/j.bcp.2011.02.017
10.1021/np50124a024
10.1016/j.cclet.2012.10.012
10.1016/j.jep.2017.03.033
10.1097/CAD.0b013e3281de7264
10.1002/mc.20272
10.1007/s10068-013-0168-8
10.1055/s-2005-916259
10.1016/j.bmc.2004.01.030
10.1002/ptr.2907
10.1016/j.fitote.2009.08.001
10.1016/j.bmcl.2010.02.068
10.3390/molecules21091240
10.1007/s13402-016-0311-7
10.1186/1472-6882-14-199
10.1080/15384047.2017.1324374
10.1016/j.bcp.2015.11.005
10.1016/j.canlet.2017.01.023
10.1142/S0192415X15500810
10.1016/j.biopha.2016.03.044
10.1016/j.tet.2017.03.064
10.1080/10408398.2015.1067595
10.1142/S0192415X01000332
10.3892/ol.2016.5387
10.1039/C7RA04322H
10.1002/ptr.5895
10.1515/znc-2007-11-1202
10.3390/ijms18071508
10.1248/bpb.34.203
10.1016/S0031-9422(01)00368-5
10.1158/1538-7445.AM2015-5541
10.3109/13880209.2013.781194
10.1016/0031-9422(95)00609-5
10.1371/journal.pone.0170551
10.3390/ijms18071403
10.3329/bjp.v11i2.25754
10.1111/1759-7714.12508
10.1021/acs.chemrestox.6b00112
10.2174/138945010791320809
10.1080/10408398.2016.1176554
10.1002/cbdv.200790083
10.1016/j.jff.2017.07.055
10.1371/journal.pone.0150235
10.1016/j.phymed.2006.01.001
10.1177/1934578X1501000924
10.1097/CAD.0000000000000224
10.3892/or.2015.4327
10.3892/ol.2016.4488
10.1016/j.fitote.2010.08.006
10.1016/j.jep.2016.08.042
10.1016/j.canlet.2017.10.041
10.1080/10286020.2010.485932
10.1080/10286020.2016.1232253
10.1007/s13277-016-5184-x
10.1055/s-2008-1081315
10.1080/10408398.2016.1231168
10.1007/s12272-001-1255-9
10.1016/j.bmcl.2005.08.099
10.3923/ijp.2017.969.979
10.1080/01635581.2014.956259
10.1021/np030481a
10.1016/j.ijbiomac.2016.06.100
10.1016/j.imlet.2005.06.008
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Keywords cancer
Cudrania tricuspidata
flavonoids
antitumor
constituent
xanthones
Language English
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References CIT0072
CIT0071
CIT0074
CIT0073
CIT0076
Kim S. J. (CIT0065) 2010; 24
CIT0075
CIT0078
CIT0111
CIT0077
CIT0110
Choi Y. H. (CIT0022) 2003; 23
CIT0070
Mu D. W. (CIT0099) 2018; 15
CIT0113
CIT0079
CIT0115
CIT0114
CIT0117
CIT0116
CIT0119
Sun Z. (CIT0127) 2006; 27
CIT0118
CIT0083
CIT0085
CIT0084
CIT0087
CIT0120
CIT0086
CIT0001
CIT0089
CIT0122
CIT0088
CIT0121
CIT0081
CIT0080
CIT0003
CIT0124
CIT0002
CIT0123
CIT0005
CIT0126
CIT0125
CIT0007
CIT0128
CIT0009
Gao M. (CIT0042) 2017; 9
CIT0008
CIT0129
CIT0093
CIT0096
CIT0095
CIT0010
CIT0098
CIT0131
CIT0097
CIT0130
Wang T. (CIT0139) 2017; 7
CIT0011
CIT0132
CIT0090
CIT0092
Denny L (CIT0032) 2012; 14
Carini F. (CIT0014) 2017; 31
Cao C. T. (CIT0012) 2015; 36
CIT0135
CIT0013
CIT0134
CIT0137
CIT0015
CIT0136
CIT0018
CIT0138
Hennen J. (CIT0045) 2009; 69
CIT0140
Ausawasamrit A. (CIT0006) 2015; 35
CIT0021
CIT0142
CIT0020
Cheok C. Y. (CIT0019) 2018; 58
CIT0023
CIT0143
CIT0025
CIT0024
CIT0145
CIT0027
CIT0148
CIT0026
CIT0147
CIT0029
CIT0028
CIT0149
CIT0030
CIT0151
CIT0150
CIT0153
CIT0031
CIT0152
Ares J. J. (CIT0004) 1996; 27
CIT0033
CIT0154
Ma N. (CIT0094) 2017; 28
CIT0036
CIT0035
CIT0156
CIT0038
CIT0159
CIT0158
CIT0039
Kim Y. S. (CIT0066) 2012; 2012
CIT0160
CIT0041
CIT0040
CIT0043
Chen X. (CIT0017) 2018; 17
CIT0047
CIT0046
CIT0049
CIT0048
Luo H. T. (CIT0091) 2012; 7
Ren J. (CIT0112) 2015; 26
Oto G. (CIT0107) 2017; 26
CIT0050
Ee G. C. (CIT0037) 2005; 22
CIT0052
CIT0051
CIT0054
CIT0053
CIT0056
CIT0055
Zhang Z. (CIT0155) 2009; 30
Xie J. J. (CIT0144) 2017; 39
CIT0058
CIT0057
CIT0059
CIT0061
CIT0060
CIT0063
CIT0062
CIT0064
CIT0067
CIT0100
Lee Y. (CIT0082) 2017; 2017
Chen S. (CIT0016) 2017; 21
CIT0109
Han Y. (CIT0044) 2016; 6
Uddin G. M. (CIT0133) 2011; 17
CIT0069
CIT0102
CIT0068
CIT0101
CIT0104
Ding H. H. (CIT0034) 2001; 23
CIT0103
CIT0106
CIT0105
CIT0108
Yamagata K. (CIT0146) 2017; 12
References_xml – volume: 39
  start-page: 602
  issue: 3
  year: 2017
  ident: CIT0144
  publication-title: Chinese Traditional Patience Medicine
  contributor:
    fullname: Xie J. J.
– ident: CIT0070
  doi: 10.1016/j.phymed.2015.07.006
– ident: CIT0128
  doi: 10.1016/j.fitote.2015.02.011
– ident: CIT0156
  doi: 10.1007/s11064-013-1119-8
– ident: CIT0151
  doi: 10.1021/np4009333
– ident: CIT0077
  doi: 10.1055/s-0033-1350619
– volume: 2017
  start-page: 1
  year: 2017
  ident: CIT0082
  publication-title: Journal of Cellular Physiology
  contributor:
    fullname: Lee Y.
– ident: CIT0086
  doi: 10.1097/00008469-200106000-00007
– ident: CIT0103
  doi: 10.1021/np068054v
– volume: 21
  start-page: 4860
  issue: 21
  year: 2017
  ident: CIT0016
  publication-title: European Review for Medical and Pharmacological Sciences
  contributor:
    fullname: Chen S.
– ident: CIT0088
  doi: 10.3390/nu3100877
– ident: CIT0020
  doi: 10.1016/j.fct.2017.12.007
– volume: 26
  start-page: 2262
  issue: 3
  year: 2017
  ident: CIT0107
  publication-title: Fresenius Environmental Bulletin
  contributor:
    fullname: Oto G.
– ident: CIT0092
  doi: 10.1016/j.foodchem.2011.03.073
– ident: CIT0149
  doi: 10.1016/j.eujim.2011.09.007
– ident: CIT0048
  doi: 10.1271/bbb.64.1038
– ident: CIT0051
  doi: 10.1021/cc0498231
– volume: 23
  start-page: 1657
  issue: 6
  year: 2003
  ident: CIT0022
  publication-title: International Journal of Oncology
  contributor:
    fullname: Choi Y. H.
– ident: CIT0052
  doi: 10.1080/10408398.2016.1252711
– ident: CIT0143
  doi: 10.1080/10519990802240387
– ident: CIT0027
  doi: 10.1002/ardp.201200440
– ident: CIT0049
  doi: 10.1248/bpb.b15-00835
– ident: CIT0137
  doi: 10.1002/ijc.25119
– ident: CIT0062
  doi: 10.3390/molecules22122130
– volume: 28
  start-page: 802
  issue: 2
  year: 2017
  ident: CIT0094
  publication-title: Biomedical Research -India
  contributor:
    fullname: Ma N.
– ident: CIT0159
  doi: 10.1002/cbdv.200490164
– ident: CIT0085
  doi: 10.4314/tjpr.v16i11.27
– ident: CIT0031
  doi: 10.1002/ptr.2286
– ident: CIT0120
  doi: 10.3184/174751913X13647406965542
– ident: CIT0036
  doi: 10.1016/j.phytol.2012.05.010
– ident: CIT0072
  doi: 10.1021/acs.jnatprod.6b00204
– ident: CIT0123
  doi: 10.1155/2014/934691
– ident: CIT0134
  doi: 10.1016/j.nut.2016.03.020
– ident: CIT0025
  doi: 10.1021/cr900019j
– ident: CIT0026
  doi: 10.1016/j.semcancer.2017.08.005
– ident: CIT0069
  doi: 10.1016/j.phymed.2013.08.018
– ident: CIT0035
  doi: 10.3390/molecules17067284
– ident: CIT0140
  doi: 10.1038/sj.onc.1209162
– ident: CIT0117
  doi: 10.1056/NEJMoa074306
– ident: CIT0040
  doi: 10.6023/cjoc201406018
– ident: CIT0125
  doi: 10.1016/j.phytochem.2004.04.025
– ident: CIT0148
  doi: 10.1021/jf202898g
– ident: CIT0158
  doi: 10.1016/j.cbi.2014.09.022
– ident: CIT0024
  doi: 10.1016/j.jcat.2003.09.012
– ident: CIT0009
  doi: 10.1016/j.ejmech.2010.06.025
– ident: CIT0010
  doi: 10.1097/CAD.0000000000000044
– ident: CIT0114
  doi: 10.1080/14786410701371041
– ident: CIT0135
  doi: 10.3329/bjp.v11i2.25549
– ident: CIT0007
  doi: 10.1016/j.ctrv.2009.11.007
– ident: CIT0008
  doi: 10.1177/1934578X1200701119
– ident: CIT0064
  doi: 10.3727/096504005776404562
– ident: CIT0102
  doi: 10.1007/s11010-017-3111-0
– volume: 30
  start-page: 601
  issue: 10
  year: 2009
  ident: CIT0155
  publication-title: World Clinical Drugs
  contributor:
    fullname: Zhang Z.
– volume: 36
  start-page: 48
  issue: 13
  year: 2015
  ident: CIT0012
  publication-title: Food Science
  contributor:
    fullname: Cao C. T.
– ident: CIT0106
  doi: 10.3109/08820139.2010.516049
– ident: CIT0021
  doi: 10.1016/j.lfs.2006.12.031
– ident: CIT0081
  doi: 10.1016/j.fct.2017.06.009
– ident: CIT0063
  doi: 10.11620/IJOB.2016.41.3.105
– ident: CIT0054
  doi: 10.14715/cmb/2018.64.1.11
– ident: CIT0098
  doi: 10.1093/annonc/mdi110
– volume: 69
  start-page: S100
  year: 2009
  ident: CIT0045
  publication-title: Cancer Research
  contributor:
    fullname: Hennen J.
– ident: CIT0115
  doi: 10.1248/bpb.b15-00767
– volume: 17
  start-page: 3239
  issue: 2
  year: 2018
  ident: CIT0017
  publication-title: Molecular Medicine Reports
  contributor:
    fullname: Chen X.
– ident: CIT0154
  doi: 10.1016/j.biopha.2017.08.048
– ident: CIT0111
  doi: 10.1016/j.biopha.2014.11.016
– volume: 2012
  issue: 1
  year: 2012
  ident: CIT0066
  publication-title: Evidence-Based Complementary and Alternative Medicine
  contributor:
    fullname: Kim Y. S.
– volume: 15
  start-page: 3202
  issue: 3
  year: 2018
  ident: CIT0099
  publication-title: Oncology Letters
  contributor:
    fullname: Mu D. W.
– ident: CIT0018
  doi: 10.3329/bjp.v8i3.14795
– ident: CIT0083
  doi: 10.4314/tjpr.v14i4.8
– ident: CIT0059
  doi: 10.1016/j.intimp.2008.11.008
– volume: 27
  start-page: 4937
  issue: 16
  year: 1996
  ident: CIT0004
  publication-title: Journal of Cheminformatics
  contributor:
    fullname: Ares J. J.
– ident: CIT0068
  doi: 10.1016/j.phymed.2016.04.007
– ident: CIT0023
  doi: 10.1007/s12272-009-1118-0
– ident: CIT0015
  doi: 10.18632/oncotarget.15264
– ident: CIT0033
  doi: 10.1016/j.lfs.2015.10.004
– ident: CIT0053
  doi: 10.1007/BF02114762
– ident: CIT0089
  doi: 10.1007/s12272-016-0761-5
– volume: 12
  start-page: 897
  issue: 6
  year: 2017
  ident: CIT0146
  publication-title: Molecular and Cellular Biochemistry
  contributor:
    fullname: Yamagata K.
– ident: CIT0153
  doi: 10.1016/j.fct.2017.08.007
– ident: CIT0100
  doi: 10.1016/j.critrevonc.2017.09.004
– ident: CIT0110
  doi: 10.2174/1381612822666160530150936
– ident: CIT0108
  doi: 10.1186/s12935-014-0124-6
– ident: CIT0067
  doi: 10.1016/j.bcp.2011.02.017
– ident: CIT0080
  doi: 10.1021/np50124a024
– ident: CIT0147
  doi: 10.1016/j.cclet.2012.10.012
– volume: 31
  start-page: 769
  issue: 3
  year: 2017
  ident: CIT0014
  publication-title: Journal of Biological Regulators & Homeostatic Agents
  contributor:
    fullname: Carini F.
– ident: CIT0096
  doi: 10.1016/j.jep.2017.03.033
– ident: CIT0113
  doi: 10.1097/CAD.0b013e3281de7264
– ident: CIT0071
  doi: 10.1002/mc.20272
– ident: CIT0087
  doi: 10.1007/s10068-013-0168-8
– ident: CIT0055
  doi: 10.1055/s-2005-916259
– ident: CIT0160
  doi: 10.1016/j.bmc.2004.01.030
– volume: 35
  start-page: 2827
  issue: 5
  year: 2015
  ident: CIT0006
  publication-title: Anti-cancer Research
  contributor:
    fullname: Ausawasamrit A.
– volume: 24
  start-page: 193
  issue: 2
  year: 2010
  ident: CIT0065
  publication-title: Phytotherapy Research
  doi: 10.1002/ptr.2907
  contributor:
    fullname: Kim S. J.
– ident: CIT0005
  doi: 10.1016/j.fitote.2009.08.001
– ident: CIT0109
  doi: 10.1016/j.bmcl.2010.02.068
– volume: 14
  start-page: 125
  issue: 75
  year: 2012
  ident: CIT0032
  publication-title: Discovery Medicine
  contributor:
    fullname: Denny L
– ident: CIT0150
  doi: 10.3390/molecules21091240
– ident: CIT0011
  doi: 10.1007/s13402-016-0311-7
– ident: CIT0121
  doi: 10.3184/174751913X13647406965542
– ident: CIT0002
  doi: 10.1186/1472-6882-14-199
– ident: CIT0003
  doi: 10.1080/15384047.2017.1324374
– ident: CIT0118
  doi: 10.1016/j.bcp.2015.11.005
– ident: CIT0029
  doi: 10.1016/j.canlet.2017.01.023
– ident: CIT0078
  doi: 10.1142/S0192415X15500810
– ident: CIT0129
  doi: 10.1016/j.biopha.2016.03.044
– ident: CIT0046
  doi: 10.1016/j.tet.2017.03.064
– ident: CIT0142
  doi: 10.1080/10408398.2015.1067595
– ident: CIT0119
  doi: 10.1142/S0192415X01000332
– ident: CIT0130
  doi: 10.3892/ol.2016.5387
– ident: CIT0145
  doi: 10.1039/C7RA04322H
– volume: 58
  start-page: 335
  issue: 3
  year: 2018
  ident: CIT0019
  publication-title: Critical Reviews in Food Science and Nutrition
  contributor:
    fullname: Cheok C. Y.
– ident: CIT0152
  doi: 10.1002/ptr.5895
– ident: CIT0056
  doi: 10.1515/znc-2007-11-1202
– ident: CIT0076
  doi: 10.3390/ijms18071508
– ident: CIT0101
  doi: 10.1248/bpb.34.203
– ident: CIT0104
  doi: 10.1016/S0031-9422(01)00368-5
– ident: CIT0097
  doi: 10.1158/1538-7445.AM2015-5541
– volume: 6
  start-page: 2755
  issue: 12
  year: 2016
  ident: CIT0044
  publication-title: American Journal of Cancer Research
  contributor:
    fullname: Han Y.
– ident: CIT0001
  doi: 10.3109/13880209.2013.781194
– ident: CIT0079
  doi: 10.1016/0031-9422(95)00609-5
– volume: 23
  start-page: 151
  issue: 2
  year: 2001
  ident: CIT0034
  publication-title: Chinese Traditional Patient Medicine
  contributor:
    fullname: Ding H. H.
– ident: CIT0124
  doi: 10.1371/journal.pone.0170551
– ident: CIT0039
  doi: 10.3390/ijms18071403
– ident: CIT0136
  doi: 10.3329/bjp.v11i2.25754
– ident: CIT0084
  doi: 10.1111/1759-7714.12508
– ident: CIT0138
  doi: 10.1021/acs.chemrestox.6b00112
– ident: CIT0090
  doi: 10.2174/138945010791320809
– ident: CIT0126
  doi: 10.1080/10408398.2016.1176554
– volume: 7
  start-page: 3951
  year: 2012
  ident: CIT0091
  publication-title: International Journal of Nanomedicine
  contributor:
    fullname: Luo H. T.
– ident: CIT0043
  doi: 10.1002/cbdv.200790083
– ident: CIT0050
  doi: 10.1016/j.jff.2017.07.055
– ident: CIT0073
  doi: 10.1371/journal.pone.0150235
– volume: 7
  start-page: 999
  issue: 4
  year: 2017
  ident: CIT0139
  publication-title: American Journal of Cancer Research
  contributor:
    fullname: Wang T.
– ident: CIT0030
  doi: 10.1016/j.phymed.2006.01.001
– ident: CIT0047
  doi: 10.1177/1934578X1501000924
– volume: 17
  start-page: 206
  issue: 3
  year: 2011
  ident: CIT0133
  publication-title: Natural Product Science
  contributor:
    fullname: Uddin G. M.
– volume: 22
  start-page: 99
  issue: 2
  year: 2005
  ident: CIT0037
  publication-title: Tropical Biomedicine
  contributor:
    fullname: Ee G. C.
– volume: 26
  start-page: 599
  issue: 6
  year: 2015
  ident: CIT0112
  publication-title: Anti-Cancer Drugs
  doi: 10.1097/CAD.0000000000000224
  contributor:
    fullname: Ren J.
– ident: CIT0116
  doi: 10.3892/or.2015.4327
– ident: CIT0013
  doi: 10.3892/ol.2016.4488
– ident: CIT0028
  doi: 10.1016/j.fitote.2010.08.006
– ident: CIT0058
  doi: 10.1016/j.jep.2016.08.042
– ident: CIT0095
  doi: 10.1016/j.canlet.2017.10.041
– ident: CIT0093
  doi: 10.1080/10286020.2010.485932
– ident: CIT0132
  doi: 10.1080/10286020.2016.1232253
– ident: CIT0061
  doi: 10.1007/s13277-016-5184-x
– volume: 27
  start-page: 207
  issue: 6
  year: 2006
  ident: CIT0127
  publication-title: Food Science
  contributor:
    fullname: Sun Z.
– ident: CIT0060
  doi: 10.1055/s-2008-1081315
– ident: CIT0041
  doi: 10.1080/10408398.2016.1231168
– ident: CIT0057
  doi: 10.1007/s12272-001-1255-9
– ident: CIT0074
  doi: 10.1016/j.bmcl.2005.08.099
– ident: CIT0105
  doi: 10.3923/ijp.2017.969.979
– ident: CIT0131
  doi: 10.1080/01635581.2014.956259
– volume: 9
  start-page: 986
  issue: 3
  year: 2017
  ident: CIT0042
  publication-title: American Journal of Translational Research
  contributor:
    fullname: Gao M.
– ident: CIT0075
  doi: 10.1021/np030481a
– ident: CIT0122
  doi: 10.1016/j.ijbiomac.2016.06.100
– ident: CIT0038
  doi: 10.1016/j.imlet.2005.06.008
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Snippet The tumor is becoming a critical threat to our lives in these years. Searching for antitumor substances from natural products is a great interest of...
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SubjectTerms Anticancer properties
Antineoplastic Agents - chemistry
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
antitumor
Antitumor activity
Antitumor agents
Bioactive compounds
Biological activity
cancer
Cell viability
constituent
Cudrania tricuspidata
Flavonoids
Flavonoids - isolation & purification
Flavonoids - pharmacology
Fruit - chemistry
Humans
Isoflavones
Molecular modelling
Moraceae - chemistry
Natural products
Plant Extracts - chemistry
Plant Extracts - pharmacology
Sustainability
Tumors
Viability
xanthones
Xanthones - isolation & purification
Xanthones - pharmacology
Title Bioactive compounds from Cudrania tricuspidata: A natural anticancer source
URI https://www.tandfonline.com/doi/abs/10.1080/10408398.2018.1541866
https://www.ncbi.nlm.nih.gov/pubmed/30582344
https://www.proquest.com/docview/2331636825
https://search.proquest.com/docview/2160150631
Volume 60
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