Reactive Oxygen Species and Their Consequences on the Structure and Function of Mammalian Spermatozoa

• Published in: Antioxidants & redox signaling
• Main Authors: Drevet, Joël R, Hallak, Jorge, Nasr-Esfahani, Mohammad-Hossein, Aitken, Robert J
• Format: Journal Article
• Language: English
• Published: United States 01.09.2022
• Subjects: sperm DNA oxidation; sperm biology; antioxidants; sperm genetic and epigenetic damage; ROS

Among the 200 or so cell types that comprise mammals, spermatozoa have an ambiguous relationship with the reactive oxygen species (ROS) inherent in the consumption of oxygen that supports aerobic metabolism. In this review, we shall see that spermatozoa need the action of ROS to reach their structur...