Catch-up antibody responses and hybrid immunity in mRNA vaccinated patients at risk of severe COVID-19

• Published in: Infectious diseases (London, England) Vol. 55; no. 10; pp. 744 - 750
• Main Authors: Al-Dury, Samer, Waldenström, Jesper, Ringlander, Johan, Einarsdottir, Sigrun, Andersson, Markus, Hamah Saed, Hevar, Waern, Johan, Martner, Anna, Hellstrand, Kristoffer, Lagging, Martin
• Format: Journal Article
• Language: English
• Published: England 03.10.2023
• Subjects: allogeneic haematopoietic stem cell transplantation; autoimmune; cirrhosis; hepatitis; hybrid immunity; Infectious Medicine; Infektionsmedicin; mRNA vaccination; SARS-CoV-2; SARS-CoV-2; autoimmune hepatitis; allogeneic haematopoietic stem cell transplantation; cirrhosis; hybrid immunity; mRNA vaccination

The immunogenicity of repeated vaccination and hybrid immunity in vulnerable patients remains unclear. We studied the impact of iterative Covid-19 mRNA vaccination and hybrid immunity on antibody levels in immunosuppressed subjects. Patients with liver cirrhosis (  = 38), survivors of allogeneic hae...