Effects of hazelnuts and cocoa on vascular reactivity in healthy subjects: a randomised study

Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study assesses the effects of hazelnuts and cocoa on vascular reactivity and metabolic profile. Sixty-one healthy volunteers, examined in a randomised,...

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Published inInternational journal of food sciences and nutrition Vol. 69; no. 2; pp. 223 - 234
Main Authors Adamo, Michela, Labate, Antonio Maria, Ferrulli, Anna, Macrì, Concetta, Terruzzi, Ileana, Luzi, Livio
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 01.03.2018
Taylor & Francis Ltd
Subjects
Adolescent
Adult
Biomarkers - blood
Blood Flow Velocity
Brachial Artery
Breakfast
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - immunology
Cardiovascular Diseases - prevention & control
cardiovascular risk
Cardiovascular system
Chocolate - analysis
Cholesterol
Cholesterol, HDL - blood
Cocoa
Corylus - chemistry
Endothelium
Female
Flavonoids
Flavonoids - therapeutic use
Food Handling
Food science
Functional Food - analysis
Hazelnuts
Health risks
High density lipoprotein
Humans
Italy - epidemiology
lipids
Male
Nuts - chemistry
Occlusion
Plant Epidermis
Randomization
Risk
Vascular Resistance
Vasodilation
Young Adult
Flavonoids
lipids
cardiovascular risk
Online AccessGet full text
ISSN0963-7486
1465-3478
1465-3478
DOI10.1080/09637486.2017.1348492

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Abstract Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study assesses the effects of hazelnuts and cocoa on vascular reactivity and metabolic profile. Sixty-one healthy volunteers, examined in a randomised, controlled, two-week intervention, received one of six breakfast integrations containing either hazelnuts, cocoa, both or none. Consumption of unpeeled hazelnuts improved HDL-cholesterol (+7.3%, p = .01 vs. baseline, p = .02 vs. control). Brachial artery peak systolic velocities (PSV) at rest increased with hazelnut integrations by 43.4% (p = .04 vs. control) and hazelnut-cocoa integrations by 26.4% (p = .01 vs. control). PSV after 3-min cuff occlusion increased by 60.7% (p = .002 vs. control) with a peeled hazelnut snack and by 64.7% with a hazelnut-cocoa integration (p = .04 vs. control). The combination hazelnut-cocoa may act in a synergic and protective way on cardiovascular system.
AbstractList Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study assesses the effects of hazelnuts and cocoa on vascular reactivity and metabolic profile. Sixty-one healthy volunteers, examined in a randomised, controlled, two-week intervention, received one of six breakfast integrations containing either hazelnuts, cocoa, both or none. Consumption of unpeeled hazelnuts improved HDL-cholesterol (+7.3%, p = .01 vs. baseline, p = .02 vs. control). Brachial artery peak systolic velocities (PSV) at rest increased with hazelnut integrations by 43.4% (p = .04 vs. control) and hazelnut-cocoa integrations by 26.4% (p = .01 vs. control). PSV after 3-min cuff occlusion increased by 60.7% (p = .002 vs. control) with a peeled hazelnut snack and by 64.7% with a hazelnut-cocoa integration (p = .04 vs. control). The combination hazelnut-cocoa may act in a synergic and protective way on cardiovascular system.
Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study assesses the effects of hazelnuts and cocoa on vascular reactivity and metabolic profile. Sixty-one healthy volunteers, examined in a randomised, controlled, two-week intervention, received one of six breakfast integrations containing either hazelnuts, cocoa, both or none. Consumption of unpeeled hazelnuts improved HDL-cholesterol (+7.3%, p = .01 vs. baseline, p = .02 vs. control). Brachial artery peak systolic velocities (PSV) at rest increased with hazelnut integrations by 43.4% (p = .04 vs. control) and hazelnut-cocoa integrations by 26.4% (p = .01 vs. control). PSV after 3-min cuff occlusion increased by 60.7% (p = .002 vs. control) with a peeled hazelnut snack and by 64.7% with a hazelnut-cocoa integration (p = .04 vs. control). The combination hazelnut-cocoa may act in a synergic and protective way on cardiovascular system.Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study assesses the effects of hazelnuts and cocoa on vascular reactivity and metabolic profile. Sixty-one healthy volunteers, examined in a randomised, controlled, two-week intervention, received one of six breakfast integrations containing either hazelnuts, cocoa, both or none. Consumption of unpeeled hazelnuts improved HDL-cholesterol (+7.3%, p = .01 vs. baseline, p = .02 vs. control). Brachial artery peak systolic velocities (PSV) at rest increased with hazelnut integrations by 43.4% (p = .04 vs. control) and hazelnut-cocoa integrations by 26.4% (p = .01 vs. control). PSV after 3-min cuff occlusion increased by 60.7% (p = .002 vs. control) with a peeled hazelnut snack and by 64.7% with a hazelnut-cocoa integration (p = .04 vs. control). The combination hazelnut-cocoa may act in a synergic and protective way on cardiovascular system.
Author Luzi, Livio
Macrì, Concetta
Ferrulli, Anna
Adamo, Michela
Terruzzi, Ileana
Labate, Antonio Maria
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/28691541$$D View this record in MEDLINE/PubMed
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Snippet Cocoa helps maintain endothelium-dependent vasodilation; consumption of hazelnuts has been associated with reduced cardiovascular disease risk. This study...
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StartPage 223
SubjectTerms Adolescent
Adult
Biomarkers - blood
Blood Flow Velocity
Brachial Artery
Breakfast
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - immunology
Cardiovascular Diseases - prevention & control
cardiovascular risk
Cardiovascular system
Chocolate - analysis
Cholesterol
Cholesterol, HDL - blood
Cocoa
Corylus - chemistry
Endothelium
Female
Flavonoids
Flavonoids - therapeutic use
Food Handling
Food science
Functional Food - analysis
Hazelnuts
Health risks
High density lipoprotein
Humans
Italy - epidemiology
lipids
Male
Nuts - chemistry
Occlusion
Plant Epidermis
Randomization
Risk
Vascular Resistance
Vasodilation
Young Adult
Title Effects of hazelnuts and cocoa on vascular reactivity in healthy subjects: a randomised study
URI https://www.tandfonline.com/doi/abs/10.1080/09637486.2017.1348492
https://www.ncbi.nlm.nih.gov/pubmed/28691541
https://www.proquest.com/docview/2011392248
https://www.proquest.com/docview/1917664104
Volume 69
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