Diagnostic pitfalls in ovarian androgen-secreting (Leydig cell) tumours: case series

• Published in: Journal of obstetrics and gynaecology Vol. 39; no. 3; p. 359
• Main Authors: Fanta, M, Fischerová, D, Indrielle-Kelly, T, Koliba, P, Zdeňková, A, Burgetová, A, Vrbíková, J
• Format: Journal Article
• Language: English
• Published: England 03.04.2019
• Subjects: Amenorrhea - etiology; Female; Hirsutism - etiology; Humans; Hysterectomy, Vaginal; Leydig Cell Tumor - diagnostic imaging; Leydig Cell Tumor - pathology; Leydig Cell Tumor - surgery; Magnetic Resonance Imaging; Middle Aged; Ovarian Neoplasms - diagnostic imaging; Ovarian Neoplasms - pathology; Ovarian Neoplasms - surgery; Ovariectomy; Positron Emission Tomography Computed Tomography; Testosterone - blood; Ultrasonography, Doppler, Color; Virilism - etiology; hirsutism; androgen; testosterone; Leydig cell tumour; hyperandrogenism; ASN; androgen-secreting ovarian tumour

Leydig cell tumours of the ovary are rare and represent a diagnostic challenge not only due to their sporadic incidence but also due to the seemingly normal imaging. We present three cases of pre- and postmenopausal women who were presented with severe clinical signs of hyperandogenism where modern...