Raman microspectroscopic model of human breast tissue: implications for breast cancer diagnosis in vivo
Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe. Understanding the chemical/morphological basis of the Raman spectrum of breast tissue is a necessary step in developing Raman spectroscopy as a to...
Saved in:
| Published in | Journal of Raman spectroscopy Vol. 33; no. 7; pp. 552 - 563 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Chichester, UK
John Wiley & Sons, Ltd
01.07.2002
|
| Online Access | Get full text |
Cover
Loading…
| Abstract | Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe. Understanding the chemical/morphological basis of the Raman spectrum of breast tissue is a necessary step in developing Raman spectroscopy as a tool for in situ breast cancer diagnosis. To understand the relationship between the Raman spectrum of a sample of breast tissue and its disease state, near‐infrared Raman spectroscopic images of human breast tissue were acquired using a confocal microscope. These images were then compared with phase contrast and hematoxylin‐ and eosin‐stained images to develop a chemical/morphological model of breast tissue Raman spectra. This model fits macroscopic tissue spectra with a linear combination of basis spectra derived from spectra of the cell cytoplasm, cell nucleus, fat, β‐carotene, collagen, calcium hydroxyapatite, calcium oxalate dihydrate, cholesterol‐like lipid deposits and water. Each basis spectrum represents data acquired from multiple patients and, when appropriate, from a variety of normal and diseased states. The model explains the spectral features of a range of normal and diseased breast tissue samples, including breast cancer. It can be used to relate the Raman spectrum of a breast tissue sample to diagnostic parameters used by pathologists. Copyright © 2002 John Wiley & Sons, Ltd. |
|---|---|
| AbstractList | Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe. Understanding the chemical/morphological basis of the Raman spectrum of breast tissue is a necessary step in developing Raman spectroscopy as a tool for in situ breast cancer diagnosis. To understand the relationship between the Raman spectrum of a sample of breast tissue and its disease state, near‐infrared Raman spectroscopic images of human breast tissue were acquired using a confocal microscope. These images were then compared with phase contrast and hematoxylin‐ and eosin‐stained images to develop a chemical/morphological model of breast tissue Raman spectra. This model fits macroscopic tissue spectra with a linear combination of basis spectra derived from spectra of the cell cytoplasm, cell nucleus, fat, β‐carotene, collagen, calcium hydroxyapatite, calcium oxalate dihydrate, cholesterol‐like lipid deposits and water. Each basis spectrum represents data acquired from multiple patients and, when appropriate, from a variety of normal and diseased states. The model explains the spectral features of a range of normal and diseased breast tissue samples, including breast cancer. It can be used to relate the Raman spectrum of a breast tissue sample to diagnostic parameters used by pathologists. Copyright © 2002 John Wiley & Sons, Ltd. Raman spectroscopy has the potential to provide real-time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe. Understanding the chemical/morphological basis of the Raman spectrum of breast tissue is a necessary step in developing Raman spectroscopy as a tool for in situ breast cancer diagnosis. To understand the relationship between the Raman spectrum of a sample of breast tissue and its disease state, near-infrared Raman spectroscopic images of human breast tissue were acquired using a confocal microscope. These images were then compared with phase contrast and hematoxylin- and eosin-stained images to develop a chemical/morphological model of breast tissue Raman spectra. This model fits macroscopic tissue spectra with a linear combination of basis spectra derived from spectra of the cell cytoplasm, cell nucleus, fat, -carotene, collagen, calcium hydroxyapatite, calcium oxalate dihydrate, cholesterol-like lipid deposits and water. Each basis spectrum represents data acquired from multiple patients and, when appropriate, from a variety of normal and diseased states. The model explains the spectral features of a range of normal and diseased breast tissue samples, including breast cancer. It can be used to relate the Raman spectrum of a breast tissue sample to diagnostic parameters used by pathologists. Abstract Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe. Understanding the chemical/morphological basis of the Raman spectrum of breast tissue is a necessary step in developing Raman spectroscopy as a tool for in situ breast cancer diagnosis. To understand the relationship between the Raman spectrum of a sample of breast tissue and its disease state, near‐infrared Raman spectroscopic images of human breast tissue were acquired using a confocal microscope. These images were then compared with phase contrast and hematoxylin‐ and eosin‐stained images to develop a chemical/morphological model of breast tissue Raman spectra. This model fits macroscopic tissue spectra with a linear combination of basis spectra derived from spectra of the cell cytoplasm, cell nucleus, fat, β‐carotene, collagen, calcium hydroxyapatite, calcium oxalate dihydrate, cholesterol‐like lipid deposits and water. Each basis spectrum represents data acquired from multiple patients and, when appropriate, from a variety of normal and diseased states. The model explains the spectral features of a range of normal and diseased breast tissue samples, including breast cancer. It can be used to relate the Raman spectrum of a breast tissue sample to diagnostic parameters used by pathologists. Copyright © 2002 John Wiley & Sons, Ltd. |
| Author | Dasari, Ramachandra R. Feld, Michael S. Shafer-Peltier, Karen E. Crowe, Joseph Fitzmaurice, Maryann Haka, Abigail S. Myles, Jonathan |
| Author_xml | – sequence: 1 givenname: Karen E. surname: Shafer-Peltier fullname: Shafer-Peltier, Karen E. organization: G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA – sequence: 2 givenname: Abigail S. surname: Haka fullname: Haka, Abigail S. organization: G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA – sequence: 3 givenname: Maryann surname: Fitzmaurice fullname: Fitzmaurice, Maryann organization: University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, USA – sequence: 4 givenname: Joseph surname: Crowe fullname: Crowe, Joseph organization: The Cleveland Clinic Foundation, Cleveland, Ohio, 44106, USA – sequence: 5 givenname: Jonathan surname: Myles fullname: Myles, Jonathan organization: The Cleveland Clinic Foundation, Cleveland, Ohio, 44106, USA – sequence: 6 givenname: Ramachandra R. surname: Dasari fullname: Dasari, Ramachandra R. organization: G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA – sequence: 7 givenname: Michael S. surname: Feld fullname: Feld, Michael S. email: msfeld@mit.edu organization: G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA |
| BookMark | eNp10L1OwzAUBWALFYm2IF7BEwwoxY6dOGFDLRRQVaTyu1mO6xSXxA52UujbkyrAxnSG--nq3jMAPWONAuAYoxFGKDxfOz9KGNsDfYxSFtAoinqgjwhjAaJJfAAG3q8RQmka4z5YLUQpDCy1dNZXStZtSFtpCUu7VAW0OXxrdiJzSvga1tr7Rl1AXVaFlqLW1niYW_c7l8JI5eBSi5WxXnuoDdzojT0E-7kovDr6ySF4ur56HN8Es_vp7fhyFkiSUhawnCEsKQqXeZZIJSWWKKYiIYKQkGKVZGyZtqeHOM6ymLY0xHmeRpGgiURCkSE46fZWzn40yte81F6qohBG2cZzEiEaRyxu4WkHd497p3JeOV0Kt-UY8V2RvC2St0W28qyTn7pQ2_8Yv1s8dDrotPa1-vrTwr3zmBEW8Zf5lOMEp6-TyZw_k28mbYao |
| CitedBy_id | crossref_primary_10_1007_s10911_006_9022_4 crossref_primary_10_1080_05704928_2015_1052817 crossref_primary_10_1007_s00216_014_7967_5 crossref_primary_10_1529_biophysj_103_038604 crossref_primary_10_1038_s41467_018_05237_x crossref_primary_10_1366_000370207781746053 crossref_primary_10_1002_jbio_201200098 crossref_primary_10_1038_s41598_017_07047_5 crossref_primary_10_1088_1612_2011_12_4_045701 crossref_primary_10_1016_j_molliq_2008_02_015 crossref_primary_10_1002_jrs_3070 crossref_primary_10_1039_B409879J crossref_primary_10_1016_j_bbamem_2006_05_007 crossref_primary_10_3390_life10090181 crossref_primary_10_7785_tcrt_2012_500325 crossref_primary_10_1007_s00216_012_5858_1 crossref_primary_10_1364_BOE_11_000200 crossref_primary_10_1021_acs_analchem_5b03696 crossref_primary_10_1016_j_jphotobiol_2009_03_002 crossref_primary_10_1038_srep09907 crossref_primary_10_1089_ast_2021_0055 crossref_primary_10_1177_1533034616655953 crossref_primary_10_1146_annurev_anchem_1_031207_112754 crossref_primary_10_1021_ac503172b crossref_primary_10_1002_jrs_4173 crossref_primary_10_1021_ac303806j crossref_primary_10_1002_jbio_201300130 crossref_primary_10_1039_C5CS00581G crossref_primary_10_1039_C8NR04677H crossref_primary_10_1002_jrs_1348 crossref_primary_10_1117_1_1920247 crossref_primary_10_1109_JSTQE_2021_3068801 crossref_primary_10_3390_biomedicines11092588 crossref_primary_10_1039_b822130h crossref_primary_10_1117_1_1928050 crossref_primary_10_1002_jbio_201600303 crossref_primary_10_1063_5_0128076 crossref_primary_10_1562_0031_8655_2003_0780517ORCAAE2_0_CO2 crossref_primary_10_1364_BOE_2_002792 crossref_primary_10_1177_153303460300200407 crossref_primary_10_1063_1_3117832 crossref_primary_10_1117_1_2815692 crossref_primary_10_1089_pho_2007_2094 crossref_primary_10_1002_jrs_5045 crossref_primary_10_1186_1476_4598_12_48 crossref_primary_10_1016_j_pdpdt_2013_01_008 crossref_primary_10_1158_0008_5472_CAN_05_2815 crossref_primary_10_1021_cr300147r crossref_primary_10_1088_0031_9155_61_23_R370 crossref_primary_10_1080_05704928_2017_1363053 crossref_primary_10_1016_S0924_2031_03_00048_1 crossref_primary_10_1039_c3an00970j crossref_primary_10_1080_14737159_2018_1439739 crossref_primary_10_3390_s16122133 crossref_primary_10_1117_1_3658756 crossref_primary_10_1080_00387010_2013_855640 crossref_primary_10_1364_BOE_5_002435 crossref_primary_10_1002_jcb_20884 crossref_primary_10_3390_s20216260 crossref_primary_10_1177_1533033818782532 crossref_primary_10_1021_acs_iecr_9b01390 crossref_primary_10_1371_journal_pone_0153599 crossref_primary_10_1194_jlr_D300022_JLR200 crossref_primary_10_1021_ac1014194 crossref_primary_10_1016_j_addr_2015_06_011 crossref_primary_10_1562_0031_8655_2003_078_0517_ORCAAE_2_0_CO_2 crossref_primary_10_3390_cancers13225682 crossref_primary_10_6000_1927_7229_2016_05_04_4 crossref_primary_10_1039_C5AN01786F crossref_primary_10_1002_jbio_202200121 crossref_primary_10_1007_s10043_014_0123_9 crossref_primary_10_1109_JSSC_2020_3046484 crossref_primary_10_1073_pnas_0501390102 crossref_primary_10_1038_s41598_018_38265_0 crossref_primary_10_1088_1612_2011_10_3_035602 crossref_primary_10_1117_1_2952297 crossref_primary_10_1117_1_2975962 crossref_primary_10_3390_ma14133732 crossref_primary_10_1016_j_pbiomolbio_2011_10_004 crossref_primary_10_1366_000370207783292082 crossref_primary_10_1016_j_spmi_2015_01_020 crossref_primary_10_1002_jrs_6562 crossref_primary_10_3389_fped_2021_777840 crossref_primary_10_1016_j_vibspec_2010_03_009 crossref_primary_10_1016_j_vibspec_2022_103489 crossref_primary_10_1002_jrs_2529 crossref_primary_10_1016_j_molliq_2011_04_021 crossref_primary_10_1080_05704920701829043 crossref_primary_10_1111_pin_12206 crossref_primary_10_1038_sj_bjc_6603102 crossref_primary_10_1038_cddis_2014_405 crossref_primary_10_1007_s10999_012_9190_x crossref_primary_10_1002_jrs_5360 crossref_primary_10_1117_1_3611010 crossref_primary_10_5802_crchim_110 crossref_primary_10_1016_j_jsb_2017_12_002 crossref_primary_10_1039_c5ib00008d crossref_primary_10_1007_s00214_009_0698_6 crossref_primary_10_1039_c2cc31845h crossref_primary_10_1007_s40766_021_00027_6 crossref_primary_10_1002_jcb_10418 crossref_primary_10_1073_pnas_1701328114 crossref_primary_10_1007_s10856_006_0438_6 crossref_primary_10_1016_j_mee_2024_112228 crossref_primary_10_1007_s10404_008_0392_3 crossref_primary_10_1016_j_ymeth_2014_02_022 crossref_primary_10_1016_j_jphotochemrev_2014_09_002 crossref_primary_10_1366_000370206777412103 crossref_primary_10_1039_b822354h crossref_primary_10_1007_s10103_016_1976_x crossref_primary_10_1039_c3an00308f crossref_primary_10_1158_0008_5472_CAN_10_1554 crossref_primary_10_3390_bios7040052 crossref_primary_10_1158_0008_5472_CAN_12_2313 crossref_primary_10_1063_1_1938667 crossref_primary_10_1021_acschemneuro_8b00235 crossref_primary_10_1364_AO_43_000542 crossref_primary_10_1002_tbio_202000018 crossref_primary_10_1016_j_saa_2021_120285 crossref_primary_10_1007_s00216_010_4283_6 crossref_primary_10_2217_14796694_4_4_501 crossref_primary_10_1016_j_saa_2021_119732 crossref_primary_10_1016_j_molstruc_2004_12_046 crossref_primary_10_1002_jrs_4693 crossref_primary_10_1067_mge_2003_105 crossref_primary_10_1002_jrs_4216 crossref_primary_10_1021_acs_analchem_7b02822 crossref_primary_10_3390_s17030627 crossref_primary_10_1364_OL_27_002004 crossref_primary_10_1039_C4AN00795F crossref_primary_10_1016_j_ymeth_2014_02_035 crossref_primary_10_1038_s41598_019_51112_0 crossref_primary_10_1016_j_bpj_2010_06_069 crossref_primary_10_1177_0003702816667516 crossref_primary_10_1016_j_cdp_2006_10_007 crossref_primary_10_2184_lsj_47_2_85 crossref_primary_10_1002_lapl_201110134 crossref_primary_10_7785_tcrt_2012_500185 crossref_primary_10_1002_jbio_200910071 crossref_primary_10_1080_05704928_2014_923902 crossref_primary_10_1002_jrs_1991 crossref_primary_10_1002_jrs_1753 crossref_primary_10_1039_b506523b crossref_primary_10_1080_05704920701551530 crossref_primary_10_1366_000370206778062147 crossref_primary_10_1364_OL_44_001383 crossref_primary_10_1080_00387010_2010_529981 crossref_primary_10_1039_c3ay40185e crossref_primary_10_1097_ALN_0000000000001249 crossref_primary_10_1002_jrs_3026 crossref_primary_10_1021_ac3011439 crossref_primary_10_1118_1_4804054 crossref_primary_10_1098_rsif_2004_0008 crossref_primary_10_1039_c2sc20316b crossref_primary_10_1117_1_2978061 crossref_primary_10_1002_jcb_20136 crossref_primary_10_1016_j_jpedsurg_2009_02_041 crossref_primary_10_1002_adhm_202301815 crossref_primary_10_1016_j_crci_2015_03_011 crossref_primary_10_1177_002215540505300114 crossref_primary_10_1039_b920229c crossref_primary_10_1016_j_canlet_2017_03_025 crossref_primary_10_1021_ac500513t crossref_primary_10_1016_j_bbagen_2012_11_023 crossref_primary_10_1080_05704928_2019_1601105 crossref_primary_10_1016_j_pdpdt_2022_102948 crossref_primary_10_5978_islsm_13_OR_05 crossref_primary_10_1039_b705029a crossref_primary_10_1117_1_JBO_23_7_071210 crossref_primary_10_1002_jrs_4897 crossref_primary_10_1039_D1NJ06187A crossref_primary_10_1021_acsanm_9b01436 crossref_primary_10_1038_srep01890 crossref_primary_10_1002_bip_20236 crossref_primary_10_1063_1_4847915 crossref_primary_10_1016_j_saa_2023_123226 crossref_primary_10_1586_14737159_8_2_149 crossref_primary_10_1080_14737159_2019_1659727 crossref_primary_10_1177_00037028211050663 crossref_primary_10_1007_s00214_011_1027_4 crossref_primary_10_1016_j_fuel_2019_116360 crossref_primary_10_1364_BOE_8_002835 crossref_primary_10_1002_bip_20586 crossref_primary_10_1002_jrs_4309 crossref_primary_10_1038_srep32922 crossref_primary_10_1177_0300060520931616 crossref_primary_10_1038_s41598_021_85758_6 crossref_primary_10_1039_b419232j crossref_primary_10_1053_tgie_2003_50004 crossref_primary_10_1002_jrs_1045 crossref_primary_10_1007_s10103_006_0432_8 crossref_primary_10_3390_molecules27249017 crossref_primary_10_1073_pnas_0509636103 crossref_primary_10_1364_OE_20_022158 crossref_primary_10_1002_jrs_4676 crossref_primary_10_1007_s10103_019_02821_5 crossref_primary_10_1364_BOE_7_002407 |
| Cites_doi | 10.1364/AO.37.001982 10.1021/ac00075a002 10.1002/1097-0142(20001001)89:7<1512::AID-CNCR14>3.0.CO;2-L 10.1016/S1054-8807(01)00063-1 10.1364/AO.40.003278 10.1366/0003702914336859 10.1366/000370290789619405 10.3322/canjclin.49.1.8 10.1016/1011-1344(92)80009-K 10.1098/rstb.1997.0047 10.1366/0003702934067072 10.1001/archsurg.134.7.712 10.1088/0031-9155/45/2/201 10.1366/0003702971938777 10.1186/bcr269 10.1111/j.1751-1097.1998.tb05159.x 10.1002/(SICI)1096-9101(1997)21:5<417::AID-LSM2>3.0.CO;2-T 10.1364/AO.35.005211 10.1016/S1054-8807(01)00064-3 10.1002/ijc.2910500408 10.1016/1011-1344(92)80008-J 10.1111/j.1751-1097.1998.tb05160.x |
| ContentType | Journal Article |
| Copyright | Copyright © 2002 John Wiley & Sons, Ltd. |
| Copyright_xml | – notice: Copyright © 2002 John Wiley & Sons, Ltd. |
| DBID | BSCLL AAYXX CITATION 7SR 7U5 8BQ 8FD JG9 L7M |
| DOI | 10.1002/jrs.877 |
| DatabaseName | Istex CrossRef Engineered Materials Abstracts Solid State and Superconductivity Abstracts METADEX Technology Research Database Materials Research Database Advanced Technologies Database with Aerospace |
| DatabaseTitle | CrossRef Materials Research Database Engineered Materials Abstracts Solid State and Superconductivity Abstracts Technology Research Database Advanced Technologies Database with Aerospace METADEX |
| DatabaseTitleList | Materials Research Database CrossRef |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry Physics |
| EISSN | 1097-4555 |
| EndPage | 563 |
| ExternalDocumentID | 10_1002_jrs_877 JRS877 ark_67375_WNG_1819XDDN_V |
| Genre | article |
| GrantInformation_xml | – fundername: NIH funderid: P41‐RR 02594. – fundername: Pathology Associates of University Hospitals. |
| GroupedDBID | -~X .3N .GA .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 31~ 33P 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHHS AANLZ AAONW AASGY AAXRX AAZKR ABCQN ABCUV ABEML ABHUG ABIJN ABJNI ABPVW ACAHQ ACBWZ ACCFJ ACCUC ACCZN ACGFS ACIWK ACPOU ACPRK ACSCC ACXBN ACXME ACXQS ADAWD ADBBV ADDAD ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEEZP AEIGN AEIMD AENEX AEQDE AETEA AEUQT AEUYR AFBPY AFFPM AFGKR AFPWT AFRAH AFVGU AFZJQ AGJLS AHBTC AI. AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB AQPKS ASPBG ATUGU AUFTA AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BSCLL BY8 CS3 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRSTM DU5 EBS EJD F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HBH HF~ HHY HHZ HVGLF HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LH5 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- P2P P2W P2X P4D PALCI Q.N Q11 QB0 QRW R.K RIWAO RJQFR RNS ROL RWI RX1 RYL SAMSI SUPJJ TUS UB1 V2E VH1 W8V W99 WBFHL WBKPD WH7 WIB WIH WIK WJL WOHZO WQJ WRC WXSBR WYISQ XG1 XPP XV2 ZZTAW ~02 ~IA ~WT AITYG HGLYW OIG WRJ AAYXX CITATION 7SR 7U5 8BQ 8FD JG9 L7M |
| ID | FETCH-LOGICAL-c3947-7f701c402dfb8cecc1c064a83a33241e8b7d9099216bb641c421ff955a48c0ae3 |
| IEDL.DBID | DR2 |
| ISSN | 0377-0486 |
| IngestDate | Sat Aug 17 00:50:20 EDT 2024 Thu Sep 26 17:18:50 EDT 2024 Sat Aug 24 01:00:25 EDT 2024 Wed Jan 17 05:01:03 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 7 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3947-7f701c402dfb8cecc1c064a83a33241e8b7d9099216bb641c421ff955a48c0ae3 |
| Notes | ark:/67375/WNG-1819XDDN-V Pathology Associates of University Hospitals. NIH - No. P41-RR 02594. istex:31DBB07392F715BAEC82EF6323B01EE0AA4E0F08 ArticleID:JRS877 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
| PQID | 35046576 |
| PQPubID | 23500 |
| PageCount | 12 |
| ParticipantIDs | proquest_miscellaneous_35046576 crossref_primary_10_1002_jrs_877 wiley_primary_10_1002_jrs_877_JRS877 istex_primary_ark_67375_WNG_1819XDDN_V |
| PublicationCentury | 2000 |
| PublicationDate | July 2002 |
| PublicationDateYYYYMMDD | 2002-07-01 |
| PublicationDate_xml | – month: 07 year: 2002 text: July 2002 |
| PublicationDecade | 2000 |
| PublicationPlace | Chichester, UK |
| PublicationPlace_xml | – name: Chichester, UK |
| PublicationTitle | Journal of Raman spectroscopy |
| PublicationTitleAlternate | J. Raman Spectrosc |
| PublicationYear | 2002 |
| Publisher | John Wiley & Sons, Ltd |
| Publisher_xml | – name: John Wiley & Sons, Ltd |
| References | Frank CJ, Redd DCB, Gansler TS, McCreery RL. R.L.M. Anal. Chem. 1994; 66: 319. Redd DCB, Feng ZC, Yue KT, Gansler TS. Appl. Spectrosc. 1993; 47: 787. Buschman HP, Motz JT, Deinum G, Romer TJ, Fitzmaurice M, Kramer JR, van der Laarse A, Bruschke AV, Feld MS. Cardio. Pathol. 2001; 10: 59. Liu CH, Das BB, Glassman WLS, Tang GC, Yoo KM, Zhu HR, Akins DL, Lubicz SS, Cleary J, Prudente R, Celmer E, Caron A, Alfano RR. J. Photochem. Photobiol. B 1992; 16: 187. Alfano RR, Liu CH, Sha WL, Zhu HR, Akins DL, Cleary J, Prudente R, Cellmer E. Lasers Life Sci. 1991; 4: 23. Manoharan R, Shafer K, Perelman L, Wu J, Chen K, Deinum G, Fitzmaurice M, Myles J, Crowe J, Dasari R, Feld M. Photochem. Photobiol. 1998; 67: 15. Radi MJ. Arch. Pathol. Lab. Med. 1989; 113: 1367. Fantini S, Walker SA, Franceschini MA, Kaschke M, Schlag PM, Moesta KT. Appl. Opt. 1998; 37: 1982. Cotran RS, Kumar V, Collins T. Robbins Pathologic Basis of Disease. Saunders: Philadelphia, PA, 1999. Kontoyannis CG, Bouropoulos NC, Koutsoukos PG. Appl. Spectrosc. 1997; 51: 64. Landis SH, Murray T, Bolden S, Wingo PA. CA-Cancer J. Clin. 1999; 49: 8. Cornelisse CJ, Kuipersdijkshoorn N, Vanvliet M, Hermans J, Devilee P. Int. J. Cancer 1992; 50: 544. Tromberg BJ, Coquoz O, Fishkin JB, Pham T, Anderson ER, Butler J, Cahn M, Gross JD, Venugopalan V, Pham D. Philos. Trans. R. Soc. London, Ser. B 1997; 661. Ntziachristos V, Chance B. Breast Cancer Res. 2001; 3: 41. Shafer-Peltier KE, Haka AS, Motz JT, Gardecki JA, Fitzmaurice M, Dasari RR, Feld MS. J. Raman Spectrosc. in preparation. Quaresima V, Matcher SJ, Ferrari M. Photochem. Photobiol. 1998; 67: 4. Sternberg SS. Histopathology for Pathologists. Lippincott-Raven: Philadelphia, PA, 1997. Zangaro RA, Silveria L, Manoharan R, Zonios G, Itzkan I, Dasari RR, Van Dam J, Feld MS. Appl. Opt. 1996; 35: 5211. Kodati VR, Tomasi GE, Turumin JL, Tu AT. Appl. Spectrosc. 1990; 44: 1408. Sharma S. Applied Multivariate Techniques. John Wiley & Sons: New York, 1996. Hebden J, Veenstra H, Dehghani H, Hillman E, Schweiger M, Arridge S, Delpy D. Appl. Opt. 2001; 40: 3278. Manoharan R, Baraga JJ, Feld MS, Rava RP. J. Photochem. Photobiol. B: Biol. 1992; 16: 211. Buschman HPJ, Deinum G, Motz JT, van der Laarse A, Bruschke AVG, Feld MS. Cardio. Pathol. 2001; 10: 69. Alini M, Losa GA. Cancer Res. 1991; 51: 1443. Kodati VR, Tomasi GE, Turumin JL, Tu AT. Appl. Spectrosc. 1991; 45: 581. Johnson J, Dalton R, Wester S, Landercasper J, Lambert P. Arch. Surg. 1999; 134: 712. Hanlon EB, Manoharan R, Koo T-W, Shafer KE, Motz JT, Fitzmaurice M, Kramer JR, Itzkan I, Dasari RR, Feld MS. Phys. Med. Biol. 2000; 45: R1. Shen K-W, Wu J, Lu J-S, Han Q-X, Shen Z-Z, Nguyen M, Shao Z-M, Barsky SH. Cancer 2000; 89: 1512. Gupta PK, Majumder SK, Uppal A. Lasers Surg. Med. 1997; 21: 417. 1991; 4 1993; 47 1997; 21 1989; 113 2000; 89 2000; 45 1999; 49 1991; 51 1997 1994; 66 1996 1995 1992; 16 1996; 35 1998; 67 2001; 40 1992; 50 1999 1998; 37 1997; 51 1990; 44 2001 1991; 45 2001; 3 1999; 134 2001; 10 Radi MJ (e_1_2_1_27_2) 1989; 113 Shafer‐Peltier KE (e_1_2_1_22_2) Cotran RS (e_1_2_1_25_2) 1999 e_1_2_1_23_2 Alini M (e_1_2_1_28_2) 1991; 51 e_1_2_1_20_2 e_1_2_1_21_2 Alfano RR (e_1_2_1_14_2) 1991; 4 e_1_2_1_29_2 Sharma S (e_1_2_1_24_2) 1996 Sternberg SS (e_1_2_1_26_2) 1997 e_1_2_1_6_2 e_1_2_1_30_2 e_1_2_1_7_2 e_1_2_1_4_2 e_1_2_1_5_2 e_1_2_1_2_2 e_1_2_1_11_2 e_1_2_1_3_2 e_1_2_1_12_2 e_1_2_1_32_2 e_1_2_1_10_2 e_1_2_1_31_2 e_1_2_1_15_2 e_1_2_1_16_2 e_1_2_1_13_2 e_1_2_1_19_2 e_1_2_1_8_2 e_1_2_1_17_2 e_1_2_1_9_2 e_1_2_1_18_2 |
| References_xml | – volume: 35 start-page: 5211 year: 1996 publication-title: Appl. Opt. – volume: 51 start-page: 64 year: 1997 publication-title: Appl. Spectrosc. – volume: 67 start-page: 4 year: 1998 publication-title: Photochem. Photobiol. – volume: 66 start-page: 319 year: 1994 article-title: R.L.M publication-title: Anal. Chem. – volume: 51 start-page: 1443 year: 1991 publication-title: Cancer Res. – publication-title: J. Raman Spectrosc. – year: 2001 – volume: 10 start-page: 69 year: 2001 publication-title: Cardio. Pathol. – year: 1996 – volume: 134 start-page: 712 year: 1999 publication-title: Arch. Surg. – volume: 16 start-page: 187 year: 1992 publication-title: J. Photochem. Photobiol. B – volume: 47 start-page: 787 year: 1993 publication-title: Appl. Spectrosc. – start-page: 661 year: 1997 publication-title: Philos. Trans. R. Soc. London, Ser. B – volume: 40 start-page: 3278 year: 2001 publication-title: Appl. Opt. – volume: 10 start-page: 59 year: 2001 publication-title: Cardio. Pathol. – volume: 45 start-page: 581 year: 1991 publication-title: Appl. Spectrosc. – volume: 37 start-page: 1982 year: 1998 publication-title: Appl. Opt. – volume: 3 start-page: 41 year: 2001 publication-title: Breast Cancer Res. – volume: 44 start-page: 1408 year: 1990 publication-title: Appl. Spectrosc. – volume: 49 start-page: 8 year: 1999 publication-title: CA–Cancer J. Clin. – volume: 113 start-page: 1367 year: 1989 publication-title: Arch. Pathol. Lab. Med. – volume: 89 start-page: 1512 year: 2000 publication-title: Cancer – volume: 16 start-page: 211 year: 1992 publication-title: J. Photochem. Photobiol. B: Biol. – year: 1997 – volume: 50 start-page: 544 year: 1992 publication-title: Int. J. Cancer – year: 1995 – volume: 45 start-page: R1 year: 2000 publication-title: Phys. Med. Biol. – volume: 67 start-page: 15 year: 1998 publication-title: Photochem. Photobiol. – volume: 21 start-page: 417 year: 1997 publication-title: Lasers Surg. Med. – volume: 4 start-page: 23 year: 1991 publication-title: Lasers Life Sci. – year: 1999 – ident: e_1_2_1_6_2 doi: 10.1364/AO.37.001982 – ident: e_1_2_1_16_2 doi: 10.1021/ac00075a002 – ident: e_1_2_1_9_2 doi: 10.1002/1097-0142(20001001)89:7<1512::AID-CNCR14>3.0.CO;2-L – volume: 4 start-page: 23 year: 1991 ident: e_1_2_1_14_2 publication-title: Lasers Life Sci. contributor: fullname: Alfano RR – ident: e_1_2_1_19_2 doi: 10.1016/S1054-8807(01)00063-1 – volume-title: Robbins Pathologic Basis of Disease year: 1999 ident: e_1_2_1_25_2 contributor: fullname: Cotran RS – ident: e_1_2_1_8_2 doi: 10.1364/AO.40.003278 – ident: e_1_2_1_30_2 doi: 10.1366/0003702914336859 – ident: e_1_2_1_29_2 doi: 10.1366/000370290789619405 – ident: e_1_2_1_2_2 doi: 10.3322/canjclin.49.1.8 – ident: e_1_2_1_18_2 doi: 10.1016/1011-1344(92)80009-K – ident: e_1_2_1_5_2 doi: 10.1098/rstb.1997.0047 – ident: e_1_2_1_15_2 doi: 10.1366/0003702934067072 – ident: e_1_2_1_3_2 doi: 10.1001/archsurg.134.7.712 – ident: e_1_2_1_13_2 doi: 10.1088/0031-9155/45/2/201 – ident: e_1_2_1_21_2 doi: 10.1366/0003702971938777 – volume: 113 start-page: 1367 year: 1989 ident: e_1_2_1_27_2 publication-title: Arch. Pathol. Lab. Med. contributor: fullname: Radi MJ – volume-title: Histopathology for Pathologists year: 1997 ident: e_1_2_1_26_2 contributor: fullname: Sternberg SS – ident: e_1_2_1_7_2 doi: 10.1186/bcr269 – ident: e_1_2_1_23_2 – ident: e_1_2_1_4_2 doi: 10.1111/j.1751-1097.1998.tb05159.x – ident: e_1_2_1_12_2 doi: 10.1002/(SICI)1096-9101(1997)21:5<417::AID-LSM2>3.0.CO;2-T – ident: e_1_2_1_10_2 doi: 10.1364/AO.35.005211 – ident: e_1_2_1_20_2 doi: 10.1016/S1054-8807(01)00064-3 – volume-title: Applied Multivariate Techniques year: 1996 ident: e_1_2_1_24_2 contributor: fullname: Sharma S – ident: e_1_2_1_32_2 doi: 10.1002/ijc.2910500408 – volume: 51 start-page: 1443 year: 1991 ident: e_1_2_1_28_2 publication-title: Cancer Res. contributor: fullname: Alini M – ident: e_1_2_1_31_2 – ident: e_1_2_1_11_2 doi: 10.1016/1011-1344(92)80008-J – ident: e_1_2_1_17_2 doi: 10.1111/j.1751-1097.1998.tb05160.x – ident: e_1_2_1_22_2 publication-title: J. Raman Spectrosc. contributor: fullname: Shafer‐Peltier KE |
| SSID | ssj0009961 |
| Score | 2.2216122 |
| Snippet | Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe.... Abstract Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber... Raman spectroscopy has the potential to provide real-time, in situ diagnosis of breast cancer during needle biopsy or surgery via an optical fiber probe.... |
| SourceID | proquest crossref wiley istex |
| SourceType | Aggregation Database Publisher |
| StartPage | 552 |
| Title | Raman microspectroscopic model of human breast tissue: implications for breast cancer diagnosis in vivo |
| URI | https://api.istex.fr/ark:/67375/WNG-1819XDDN-V/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fjrs.877 https://search.proquest.com/docview/35046576 |
| Volume | 33 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB5VINReyqOt2NKHD4hblk3ixAk3xKMIqXvYFrrqxbIdGwVEgjZZhPrrO-NsYKlUqeopB9tKMjOOP8fffAOwi2tgonlOQreOB9ylaZAr4wJhYmeNti5zlDv8dZyeXfDzaTJdKvXV6UM8_nCjmeG_1zTBlW72n0RDr2fNMBOUR04yegSHJk_CUYjifa28WIiAROW6dFkaub8Y92wdWiWTPjwDmctQ1a81p-vws3_KjmJyM5y3emh-_SHg-F-vsQGvFwiUHXYhswkvbLUFL4_6wm9bsOZZoaZ5A1cTdasqdkukPZ-SSdKX9V1pmC-gw2rHfI0_pona3rLWe_GAlUs0dYaouG83FGIzVnT0vrJhZcXuy_v6LVycnnw_OgsWlRkCE-dcBMKJUWhw61k4nRmMgtAgtFFZrGIEaKHNtChydEIUplqnHLtGoXN5kiiemZGy8TtYqerKbgMrbM7pkEFHKke0UChVRCNeCGWjwloVDoD1fpJ3nQCH7KSWI4m2k2i7Aex5_z22q9kN8dVEIn-Mv0jEMPn0-HgsLwfwuXewRJvS0YiqbD1vZJyMeIpbrwHsemf97VbyfPINL-__rdsOvPLFYzy79wOstLO5_YgYptWffLj-BuZW8YY |
| link.rule.ids | 315,786,790,1382,27955,27956,46327,46751 |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB1BK1QuFAoVC_3woeKW7SZx4oQb6rZdSruHpYWVOFi2Y6NQNal2sxXi1zPjbPqBhIQ45eBYSWbG8bP95g3AHs6BieY5Cd06HnCXpkGujAuEiZ012rrMUe7w2TgdXfCTaTJdsiopF6bVh7jdcKOR4f_XNMBpQ3r_TjX0x2zez4R4DKs42BMalMPJnXQU4nhfLS8WIiBZuTZhlrruLzs-mIlWyag_H8DM-2DVzzZH6_Cte8-WZHLZXzS6b379IeH4fx_yHJ4tQSj70EbNC3hkqw1YO-hqv23AE08MNfOX8H2irlTFroi357MySf2yvi4N8zV0WO2YL_PHNLHbG9Z4R75n5T2mOkNg3LUbirIZK1qGXzlnZcVuypv6FVwcHZ4fjIJlcYbAxDkXgXBiEBpcfRZOZwYDITSIblQWqxgxWmgzLYocvRCFqdYpx1uj0Lk8SRTPzEDZeBNWqrqyr4EVNud0zqAjlSNgKJQqogEvhLJRYa0Ke8A6R8nrVoNDtmrLkUTbSbRdD955B962q9klUdZEIr-OjyXCmHw6HI7llx7sdh6WaFM6HVGVrRdzGScDnuLqqwd73lt_e5Q8mXzGy5t_u20X1kbnZ6fy9OP401t46mvJeLLvFqw0s4XdRkjT6B0fu78B-w_1pg |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3PT9swFH5ioP24wMY2rQOGD2i3lCZx4mQ3RCkMWDV1Y6u4WP45ZYikalM07a_fs9NAmYQ07ZSDbSV57zn-HH_vewB7uAYmkuZO6NbSgNo0DXKhbMBUbI2SxmbW5Q5_GqYnF_R0nIyXSn01-hC3P9zczPDfazfBJ9ru34mG_pzOuhljj2CNpnHk9l390Z1yFMJ4XywvZixwqnJNvqwbur8YeG8hWnM2_XUPZS5jVb_YDDbgsn3MhmNy1Z3Xsqt-_6Xg-F_v8RzWFxCUHDQx8wJWTLkJTw_bym-b8NjTQtXsJfwYiWtRkmvH2vM5mU77spoUivgKOqSyxBf5I9Jx22tSezd-IMUST50gLG7blYuxKdENv6-YkaIkN8VN9QouBkdfD0-CRWmGQMU5ZQGzrBcq3HtqKzOFYRAqxDYii0WMCC00mWQ6RydEYSplSrFrFFqbJ4mgmeoJE7-G1bIqzRsg2uTUnTLISOQIF7QQOupRzYSJtDEi7ABp_cQnjQIHb7SWI46242i7Drz3_rttF9MrR1hjCf8-POYIYvJxvz_k3zqw2zqYo03d2YgoTTWf8Tjp0RT3Xh3Y88566Fb8dPQFL2__rdsuPPncH_Dzj8OzLXjmC8l4pu82rNbTudlBPFPLdz5y_wAzkvRV |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Raman+microspectroscopic+model+of+human+breast+tissue%3A+implications+for+breast+cancer+diagnosis+in+vivo&rft.jtitle=Journal+of+Raman+spectroscopy&rft.au=Shafer%E2%80%90Peltier%2C+Karen+E.&rft.au=Haka%2C+Abigail+S.&rft.au=Fitzmaurice%2C+Maryann&rft.au=Crowe%2C+Joseph&rft.date=2002-07-01&rft.issn=0377-0486&rft.eissn=1097-4555&rft.volume=33&rft.issue=7&rft.spage=552&rft.epage=563&rft_id=info:doi/10.1002%2Fjrs.877&rft.externalDBID=n%2Fa&rft.externalDocID=10_1002_jrs_877 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0377-0486&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0377-0486&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0377-0486&client=summon |