Benefits in Cognitive Function, Blood Pressure, and Insulin Resistance Through Cocoa Flavanol Consumption in Elderly Subjects With Mild Cognitive Impairment: The Cocoa, Cognition, and Aging (CoCoA) Study

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 60; no. 3; pp. 794 - 801
• Main Authors: Desideri, Giovambattista, Kwik-Uribe, Catherine, Grassi, Davide, Necozione, Stefano, Ghiadoni, Lorenzo, Mastroiacovo, Daniela, Raffaele, Angelo, Ferri, Livia, Bocale, Raffaella, Lechiara, Maria Carmela, Marini, Carmine, Ferri, Claudio
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD American Heart Association, Inc 01.09.2012; Lippincott Williams & Wilkins
• Subjects: Aged; Aged, 80 and over; Aging - physiology; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Blood Pressure - drug effects; Blood Pressure - physiology; Cacao; Cardiology. Vascular system; Clinical manifestations. Epidemiology. Investigative techniques. Etiology; Cognition - drug effects; Cognition - physiology; Cognition Disorders - diet therapy; Cognition Disorders - physiopathology; Cognition Disorders - prevention & control; Dose-Response Relationship, Drug; Double-Blind Method; Eating; Female; Flavanones - administration & dosage; Flavanones - pharmacology; Flavanones - therapeutic use; Follow-Up Studies; Humans; Insulin Resistance - physiology; Intelligence Tests; Lipid Peroxidation - drug effects; Lipid Peroxidation - physiology; Male; Medical sciences; Middle Aged; Treatment Outcome; Human; Hypertension; cognitive function; Senescence; cocoa flavanols; Cardiovascular disease; Arterial pressure; Cognition; Blood pressure; mild cognitive impairment; Insulin; Elderly

Flavanol consumption is favorably associated with cognitive function. We tested the hypothesis that dietary flavanols might improve cognitive function in subjects with mild cognitive impairment. We conducted a double-blind, parallel arm study in 90 elderly individuals with mild cognitive impairment...