Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis

• Published in: European journal of clinical microbiology & infectious diseases Vol. 31; no. 6; pp. 1271 - 1277
• Main Authors: Gasparoto, T. H., de Oliveira, C. E., Vieira, N. A., Porto, V. C., Cunha, F. Q., Garlet, G. P., Campanelli, A. P., Lara, V. S.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.06.2012; Springer; Springer Nature B.V
• Subjects: Adult; Age; Age Factors; Aged; Aged, 80 and over; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Blood; Blood - immunology; Candida albicans; Candida albicans - immunology; Candida albicans - pathogenicity; Candidiasis, Oral - immunology; Cell activation; Cells, Cultured; Cytokines - secretion; Dentistry; Dentures; Elastase; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Geriatrics; Granulocyte-macrophage colony-stimulating factor; Humans; Infectious diseases; Interleukin 10; Interleukin 4; Internal Medicine; Leukocytes (neutrophilic); Male; Medical Microbiology; Medical sciences; Middle Aged; Neutrophil Activation; Neutrophils; Non tumoral diseases; Oral infection; Otorhinolaryngology. Stomatology; Pancreatic Elastase - metabolism; Peroxidase; Peroxidase - metabolism; Prosthodontics; Research Article; Stomatitis; Stomatitis, Denture - immunology; Brazil; Blood Neutrophil; Elderly Group; Young Control; Elderly Individual; Elastase Activity; Human; Candidiasis; Mycosis; Microbiology; Stomatology; Blood; Fungi; Infection; Stomatitis; Candida; Oral cavity disease; Fungi Imperfecti; Neutrophil; Elderly

We have identified impaired neutrophils in elderly individuals which could be involved with Candida -related denture stomatitis (DS), an oral infection predominantly caused by Candida albicans , affecting especially elderly individuals using dental prosthesis. However, specific mechanisms performed...