Determinants of subacute response to clopidogrel: relative impact of CYP2C19 genotype and PGE1/adenylate cyclase signalling - Hurst, Nicola L.; Nooney, Vivek B.; Chirkov, Yuliy Y.; De Caterina, Raffaele; Horowitz, John D. (Thrombosis research, 2015)
Keywords: adenylate cyclase; Adenylyl Cyclases - metabolism; Adult; Aged; Aged, 80 and over; Alprostadil - metabolism; blood platelets; clopidogrel; cyclic AMP; Cytochrome P-450 CYP2C19 - genetics; Female; Genotype; Hematology, Oncology and Palliative Medicine; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors - pharmacology; purinergic P2Y12 receptor antagonists; Signal Transduction; Ticlopidine - analogs & derivatives; Ticlopidine - pharmacology; clopidogrel; cyclic AMP; blood platelets; purinergic P2Y12 receptor antagonists; adenylate cyclase; purinergic P2Y 12 receptor antagonists; purinergic P2Y receptor antagonists