Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation - Cahova, Monika; Palenickova, Eliska; Dankova, Helena; Sticova, Eva; Burian, Martin; Drahota, Zdenek; Cervinkova, Zuzana; Kucera, Otto; Gladkova, Christina; Stopka, Pavel; Krizova, Jana; Papackova, Zuzana; et al. (American journal of physiology: Gastrointestinal and liver physiology, 2015)
Keywords: Adenosine Triphosphate - metabolism; Animals; Anti-Inflammatory Agents - pharmacology; Antioxidants; Antioxidants - pharmacology; Apoptosis - drug effects; Cytoprotection; Diet, High-Fat; Disease Models, Animal; DNA damage; Energy Metabolism - drug effects; Enzymes; Inflammation Mediators - metabolism; Lipid Peroxidation - drug effects; Liver - drug effects; Liver - metabolism; Liver - pathology; Liver diseases; Male; Metformin - pharmacology; Mitochondria; Mitochondria, Liver - drug effects; Mitochondria, Liver - metabolism; Mitochondria, Liver - pathology; Non-alcoholic Fatty Liver Disease - drug therapy; Non-alcoholic Fatty Liver Disease - etiology; Non-alcoholic Fatty Liver Disease - metabolism; Non-alcoholic Fatty Liver Disease - pathology; Oxidative stress; Oxidative Stress - drug effects; Physiology; Rats, Wistar; Reactive Oxygen Species - metabolism; Reperfusion Injury - etiology; Reperfusion Injury - metabolism; Reperfusion Injury - pathology; Reperfusion Injury - prevention & control; Time Factors; metformin; liver injury; 31P MR spectroscopy; oxidative stress; mitochondrial respiration