Identification of HnRNP M as a novel biomarker for colorectal carcinoma by quantitative proteomics

• Published in: American journal of physiology: Gastrointestinal and liver physiology Vol. 306; no. 5; pp. G394 - G403
• Main Authors: Chen, Shuijiao, Zhang, Jie, Duan, Lunxi, Zhang, Yu, Li, Cui, Liu, Deliang, Ouyang, Chunhui, Lu, Fanggen, Liu, Xiaowei
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.03.2014
• Subjects: Biomarkers; Biomarkers, Tumor; Cell Line, Tumor; Colorectal cancer; Colorectal Neoplasms - blood; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - metabolism; Correlation analysis; Female; Gene Expression Regulation, Neoplastic - physiology; Heterogeneous-Nuclear Ribonucleoprotein Group M - genetics; Heterogeneous-Nuclear Ribonucleoprotein Group M - metabolism; Humans; Male; Medical treatment; Metastasis; Middle Aged; Protein expression; Proteomics - methods; RNA, Small Interfering; heterogeneous nuclear ribonucleoprotein M

Colorectal carcinoma (CRC) is one of the most common cancers in the world, and identification of new CRC biomarkers will be helpful for the diagnosis and treatment of CRC. For isobaric tags for relative and absolute quantitation (iTRAQ) analysis, fresh CRC and adjacent, colonic adenoma, ulcerative c...