Antibiotic use in prevention of anal fistulas following incision and drainage of anorectal abscesses: A systematic review and meta-analysis

• Published in: The American journal of surgery Vol. 217; no. 5; pp. 910 - 917
• Main Authors: Mocanu, Valentin, Dang, Jerry T., Ladak, Farah, Tian, Chunhong, Wang, Haili, Birch, Daniel W., Karmali, Shahzeer
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2019; Elsevier Limited
• Subjects: Abscess - therapy; Abscesses; Age; Anorectal; Antibiotic Prophylaxis; Antibiotics; Bias; Clinical trials; Complications; Diabetes; Disease control; Drainage; English language; Etiology; Fistula; Fistulae; Guidelines; Humans; Literature reviews; Meta-analysis; Morbidity; Patients; Postoperative Complications - prevention & control; Prevention; Rectal Diseases - therapy; Rectal Fistula - prevention & control; Sepsis; Statistical analysis; Studies; Surgeons; Surgery; Systematic review; Wound drainage

Treatment of anorectal abscesses continues to revolve around early surgical drainage and control of perianal sepsis. Yet even with prompt drainage, abscess recurrence and postoperative fistula formation rates are as high as 40% within 12 months. These complications are thought to be associated with...