Liquid biopsy for lung cancer early detection

• Published in: Journal of thoracic disease Vol. 10; no. S7; pp. S882 - S897
• Main Authors: Santarpia, Mariacarmela, Liguori, Alessia, D’Aveni, Alessandro, Karachaliou, Niki, Gonzalez-Cao, Maria, Daffinà, Maria Grazia, Lazzari, Chiara, Altavilla, Giuseppe, Rosell, Rafael
• Format: Journal Article
• Language: English
• Published: China AME Publishing Company 01.04.2018
• Subjects: Review; circulating cell-free tumor DNA; liquid biopsy; Early-stage non-small cell lung cancer (Early-stage NSCLC)

Molecularly targeted therapies and immune checkpoint inhibitors have markedly improved the therapeutic management of advanced lung cancer. However, it still remains the leading cause of cancer-related mortality worldwide, with disease stage at diagnosis representing the main prognostic factor. Detec...