Smoking, chromosomal aberrations, and cancer incidence in healthy subjects

• Published in: Mutation research. Genetic toxicology and environmental mutagenesis Vol. 867; p. 503373
• Main Authors: Farkas, Gyöngyi, Kocsis, Zsuzsa S., Székely, Gábor, Dobozi, Mária, Kenessey, István, Polgár, Csaba, Jurányi, Zsolt
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.07.2021
• Subjects: Aneuploidy; Cytogenetic analysis; Human lymphocyte; Neoplasm; Risk assessment; Neoplasm; Cytogenetic analysis; Aneuploidy; Risk assessment; Human lymphocyte

•Chromatid breaks and total aberration frequency were higher in smokers compared to non-smokers.•Intensity of smoking was a predictor of the frequency of chromosomal aberrations, while duration was not.•Relative risk of cancer incidence was 1.74 (95 % CI 1.08−2.77, p = 0.019) for very heavy smokers....