Insight into the Development of PET Radiopharmaceuticals for Oncology

• Published in: Cancers Vol. 12; no. 5; p. 1312
• Main Authors: Lau, Joseph, Rousseau, Etienne, Kwon, Daniel, Lin, Kuo-Shyan, Bénard, François, Chen, Xiaoyuan
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 21.05.2020
• Subjects: Review; radiopharmaceuticals; positron emission tomography; diagnostic imaging; radiochemistry; personalized medicine

While the development of positron emission tomography (PET) radiopharmaceuticals closely follows that of traditional drug development, there are several key considerations in the chemical and radiochemical synthesis, preclinical assessment, and clinical translation of PET radiotracers. As such, we o...