Endometrial cell‑derived exosomes facilitate the development of adenomyosis via the IL‑6/JAK2/STAT3 pathway

• Published in: Experimental and therapeutic medicine Vol. 26; no. 5
• Main Authors: Jiang, Xinchan, Chen, Xiaobo
• Format: Journal Article
• Language: English
• Published: Athens Spandidos Publications 01.11.2023; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Apoptosis; Cell adhesion & migration; Cell cycle; Cell growth; Cell organelles; Development and progression; Endometriosis; Endometrium; Flow cytometry; Health aspects; Interleukin-6; Interleukins; Kinases; Monoclonal antibodies; Pathogenesis; Physiological aspects; Proteins; Scientific equipment and supplies industry; Uterus; China; United States

Interleukin (IL)-6 upregulation is involved in the pathogenesis of adenomyosis, but the underlying mechanism remains to be elucidated. Exosomes mediate intercellular communication, therefore the present study investigated whether endometrial cell-derived exosomes mediated the crosstalk between the e...