Concentration of Gallbladder Phosphatidylcholine in Cholangiopathies: A Phosphorus‐31 Magnetic Resonance Spectroscopy Pilot Study

• Published in: Journal of magnetic resonance imaging Vol. 55; no. 2; pp. 530 - 540
• Main Authors: Pfleger, Lorenz, Halilbasic, Emina, Gajdošík, Martin, Benčíková, Diana, Chmelík, Marek, Scherer, Thomas, Trattnig, Siegfried, Krebs, Michael, Trauner, Michael, Krššák, Martin
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.02.2022; Wiley Subscription Services, Inc
• Subjects: Adenosine triphosphate; Adult; Age; ATP; Bile ducts; Biomarkers; cholangiopathy; Cholangitis; Cholangitis, Sclerosing; Female; Field strength; Gallbladder; Humans; Image acquisition; In vivo methods and tests; Lecithin; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Metabolites; Middle Aged; Pathogenesis; Phosphatidylcholine; Phosphatidylcholines; Phosphorus; Pilot Projects; Relaxation time; Resonance; Spectral resolution; Spectroscopy; Spectrum analysis; Statistical analysis; Statistical tests; Subgroups; T1 relaxation; cholangiopathy; magnetic resonance spectroscopy; gallbladder; phosphatidylcholine; T1 relaxation; phosphorus

Background Biliary phosphatidylcholine (PtdC) concentration plays a role in the pathogenesis of bile duct diseases. In vivo phosphorus‐31 magnetic resonance spectroscopy (31P‐MRS) at 7 T offers the possibility to assess this concentration noninvasively with high spectral resolution and signal intens...