Proteomic characterization of human sperm plasma membrane‐associated proteins and their role in capacitation

• Published in: Andrology (Oxford) Vol. 8; no. 1; pp. 171 - 180
• Main Authors: Hernández‐Silva, Gabriela, Fabián López‐Araiza, Jorge Elías, López‐Torres, Aideé Saray, Larrea, Fernando, Torres‐Flores, Víctor, Chirinos, Mayel
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2020
• Subjects: capacitation; Cell Membrane - metabolism; decapacitation factor; Humans; Male; male reproductive tract; Mass spectrometry; Membrane Proteins - metabolism; Motility; Phosphorylation; Proteins; Proteome; Scientific imaging; Sperm; Sperm Capacitation; spermatozoa; Spermatozoa - metabolism; capacitation; decapacitation factor; spermatozoa; male reproductive tract

Background Plasma membranes of ejaculated sperm are covered by epididymal and accessory glands secreted proteins that must be released from sperm surface during the female reproductive tract passage in order to capacitate and fertilize the oocyte. Objectives As human sperm plasma membrane‐associated...