Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation

• Published in: Medical physics (Lancaster) Vol. 40; no. 11; pp. 112507 - n/a
• Main Authors: Chan, Chung, Jin, Xiao, Fung, Edward K., Naganawa, Mika, Mulnix, Tim, Carson, Richard E., Liu, Chi
• Format: Journal Article
• Language: English
• Published: United States American Association of Physicists in Medicine 01.11.2013
• Subjects: Analysis of motion; Anatomy; Biological material, e.g. blood, urine; Haemocytometers; Cancer; Carcinoma, Non-Small-Cell Lung - diagnostic imaging; Computed tomography; Computerised tomographs; computerised tomography; correlation methods; Coupled channel methods; Digital computing or data processing equipment or methods, specially adapted for specific applications; edge detection; Fluorine Radioisotopes - chemistry; Healthy Volunteers; Humans; Hypoxia; Image data processing or generation, in general; image denoising; Image enhancement or restoration, e.g. from bit‐mapped to bit‐mapped creating a similar image; Image Processing, Computer-Assisted; image reconstruction; Image reconstruction; tomography; Imaging, Three-Dimensional; Insulin-Secreting Cells - diagnostic imaging; INTEX; kidney; Kidney - diagnostic imaging; Kidneys; Lung Neoplasms - diagnostic imaging; Measuring half‐life of a radioactive substance; Medical image noise; medical image processing; Medical image reconstruction; Medical imaging; Misonidazole - analogs & derivatives; Misonidazole - chemistry; motion compensation; Movement; Pancreas - diagnostic imaging; PET/CT; phantoms; Pneumodyamics, respiration; pneumodynamics; Positron emission tomography (PET); Positron-Emission Tomography; Regression Analysis; Reproducibility of Results; Respiration; respiratory motion correction; Scintigraphy; Signal Processing, Computer-Assisted; Tetrabenazine - analogs & derivatives; Tetrabenazine - chemistry; three‐dimensional internal‐external motion correlation; tumours; X-Ray Microtomography; respiratory motion correction; three-dimensional internal-external motion correlation; INTEX; PET/CT

Purpose: Respiratory motion during PET/CT imaging can cause substantial image blurring and underestimation of tracer concentration for both static and dynamic studies. In this study, the authors developed an event-by-event respiratory motion correction method that used three-dimensional internal-one...