Assessment of segmental myocardial blood flow and myocardial perfusion reserve by adenosine‐stress myocardial arterial spin labeling perfusion imaging

• Published in: Journal of magnetic resonance imaging Vol. 46; no. 2; pp. 413 - 420
• Main Authors: Yoon, Andrew J., Do, Hung Phi, Cen, Steven, Fong, Michael W., Saremi, Farhood, Barr, Mark L., Nayak, Krishna S.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.08.2017
• Subjects: Adenosine; Adenosine - chemistry; Adult; arterial spin labeling; Arteries - diagnostic imaging; Blood flow; Blood Pressure; Coronary Circulation - physiology; Feasibility Studies; Female; Functional magnetic resonance imaging; Healthy Volunteers; Heart - diagnostic imaging; Heart diseases; Human performance; Humans; Magnetic Resonance Imaging; Male; myocardial blood flow; Myocardial Perfusion Imaging; myocardial perfusion reserve; Myocardium; Myocardium - pathology; NMR; Nuclear magnetic resonance; Oxygen - analysis; Oxygen - blood; Oxygenation; Perfusion; Precession; Reproducibility of Results; Resonance; Segments; Signal-To-Noise Ratio; Spin labeling; Spin Labels; Statistical analysis; Statistical significance; Stress; Stresses; Territory; Vasodilator Agents - chemistry; Young Adult; myocardial perfusion reserve; arterial spin labeling; myocardial blood flow

Purpose To determine the feasibility of measuring increases in myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) on a per‐segment basis using arterial spin labeled (ASL) magnetic resonance imaging (MRI) with adenosine vasodilator stress in normal human myocardium. Materials and Meth...