Flow-Mediated Dilation and Cardiovascular Event Prediction: Does Nitric Oxide Matter?

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 57; no. 3; pp. 363 - 369
• Main Authors: Green, Daniel J., Jones, Helen, Thijssen, Dick, Cable, N.T., Atkinson, Greg
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD American Heart Association, Inc 01.03.2011; Lippincott Williams & Wilkins
• Subjects: Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Blood Flow Velocity - physiology; Blood vessels and receptors; Cardiology. Vascular system; Cardiovascular Diseases - metabolism; Cardiovascular Diseases - physiopathology; Endothelium, Vascular - metabolism; Endothelium, Vascular - physiopathology; Fundamental and applied biological sciences. Psychology; Humans; Medical sciences; Nitric Oxide - metabolism; Predictive Value of Tests; Risk Factors; Vasodilation - physiology; Vertebrates: cardiovascular system; Hypertension; NO; Methodology; Nitric oxide; Predictive value; Cardiovascular disease; flow-mediated dilation; cuff placement

Endothelial dysfunction is an early atherosclerotic event that precedes clinical symptoms and may also render established plaque vulnerable to rupture. Noninvasive assessment of endothelial function is commonly undertaken using the flow-mediated dilation (FMD) technique. Some studies indicate that F...