Role of Stem Cells in Pathophysiology and Therapy of Spondyloarthropathies-New Therapeutic Possibilities?

• Published in: International journal of molecular sciences Vol. 19; no. 1; p. 80
• Main Authors: Krajewska-Włodarczyk, Magdalena, Owczarczyk-Saczonek, Agnieszka, Placek, Waldemar, Osowski, Adam, Engelgardt, Piotr, Wojtkiewicz, Joanna
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.12.2017; MDPI
• Subjects: Ankylosing spondylitis; Arthritis; Bone growth; Inflammation; Interleukin 12; Interleukin 17; mesenchymal stem cells; Mesenchyme; Osteogenesis; Pathogenesis; Psoriatic arthritis; Review; Spondylitis; spondyloarthropathies; Spondyloarthropathy; Stem cells; Stromal cells; Tumor necrosis factor; Tumor necrosis factor-α; inflammation; mesenchymal stem cells; spondyloarthropathies

Considerable progress has been made recently in understanding the complex pathogenesis and treatment of spondyloarthropathies (SpA). Currently, along with traditional disease modifying anti-rheumatic drugs (DMARDs), TNF-α, IL-12/23 and IL-17 are available for treatment of such diseases as ankylosing...