Cancer metastasis: Mechanisms of inhibition by melatonin

• Published in: Journal of pineal research Vol. 62; no. 1; pp. np - n/a
• Main Authors: Su, Shih‐Chi, Hsieh, Ming‐Ju, Yang, Wei‐En, Chung, Wen‐Hung, Reiter, Russel J., Yang, Shun‐Fa
• Format: Journal Article
• Language: English
• Published: England 01.01.2017
• Subjects: angiogenesis; Animals; epithelial–mesenchymal transition; Humans; matrix metalloproteinase; melatonin; Melatonin - metabolism; metastasis; Neoplasm Metastasis - pathology; matrix metalloproteinase; epithelial-mesenchymal transition; melatonin; metastasis; angiogenesis

Melatonin is a naturally occurring molecule secreted by the pineal gland and known as a gatekeeper of circadian clocks. Mounting evidence indicates that melatonin, employing multiple and interrelated mechanisms, exhibits a variety of oncostatic properties in a myriad of tumors during different stage...