Artemongolins A–K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities

• Published in: Archives of pharmacal research Vol. 46; no. 9-10; pp. 782 - 794
• Main Authors: Shang, Chong, Ma, Yun-Bao, Wang, Yuan, He, Xiao-Feng, Li, Tian-Ze, Chen, Ji-Jun
• Format: Journal Article
• Language: English
• Published: Seoul Pharmaceutical Society of Korea 01.10.2023; 대한약학회
• Subjects: Artemisia; germacrene; hepatoma; humans; Medicine; Pharmacology/Toxicology; Pharmacy; Research Article; spectral analysis; X-ray diffraction; 약학; K; Antihepatoma activity; Sesquiterpenoid dimers; Artemongolins A

Artemongolins A – K ( 1–11 ), which are undescribed sesquiterpenoid dimers, were obtained from Artemisia mongolica and characterized through comprehensive spectral data, including HRESIMS, IR, 1D and 2D NMR, and ECD calculations. The absolute configurations of compounds 1 , 4 , and 7 were undoubtedl...