Analysis of the molecular response of Pseudomonas putida KT2440 to the next-generation biofuel n-butanol

• Published in: Journal of proteomics Vol. 122; pp. 11 - 25
• Main Authors: Simon, Oliver, Klebensberger, Janosch, Mükschel, Björn, Klaiber, Iris, Graf, Nadja, Altenbuchner, Josef, Huber, Armin, Hauer, Bernhard, Pfannstiel, Jens
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 03.06.2015
• Subjects: 1-Butanol - metabolism; alcohol dehydrogenase; bacteria; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; beta acids; beta oxidation; Biocatalysis; biocatalysts; Biofuel; Biofuels; butanol; cost effectiveness; energy costs; fatty acids; fermentation; hosts; Lipid Metabolism; mutants; n-butanol; oxidation; Phospholipids; proteins; proteome; Proteome - genetics; Proteome - metabolism; proteomics; Pseudomonas putida; Pseudomonas putida - genetics; Pseudomonas putida - metabolism; Pseudomonas putida KT2440; Quantitative proteomics; solvents; surveys; taxonomic keys; toxicity; n-butanol; Biofuel; Phospholipids; Biocatalysis; Quantitative proteomics; Pseudomonas putida KT2440

To increase the efficiency of biocatalysts a thorough understanding of the molecular response of the biocatalyst to precursors, products and environmental conditions applied in bioconversions is essential. Here we performed a comprehensive proteome and phospholipid analysis to characterize the molec...