Multicentre assessment of motor and sensory evoked potentials in multiple sclerosis: reliability and implications for clinical trials

• Published in: Multiple sclerosis journal - experimental, translational and clinical Vol. 5; no. 2; p. 2055217319844796
• Main Authors: Hardmeier, Martin, Jacques, François, Albrecht, Philipp, Bousleiman, Habib, Schindler, Christian, Leocani, Letizia, Fuhr, Peter
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.04.2019; Sage Publications Ltd
• Subjects: Biomarkers; Clinical trials; Multiple sclerosis; Original Research Paper; progressive MS; response biomarker; sensory evoked potentials; Motor evoked potentials; test–retest reliability; biomarker; mean detectable change; remyelination

Background Motor and sensory evoked potentials (EP) are potential candidate biomarkers for clinical trials in multiple sclerosis. Objective To determine test -retest reliability of motor EP (MEP) and sensory EP (SEP) and associated EP-scores in patients with multiple sclerosis. Methods In three cent...