Systemic analysis of the prognostic significance and interaction network of miR-26b-3p in cholangiocarcinoma

• Published in: Applied biochemistry and biotechnology Vol. 196; no. 7; pp. 4166 - 4187
• Main Authors: Yan, Xijing, Hu, Zhongying, Li, Xuejiao, Liang, Jinliang, Zheng, Jun, Gong, Jiao, Hu, Kunpeng, Sui, Xin, Li, Rong
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2024; Springer Nature B.V
• Subjects: Bile Duct Neoplasms - genetics; Bile Duct Neoplasms - metabolism; Bile Duct Neoplasms - pathology; Biochemistry; Biomarkers; Biomarkers, Tumor - genetics; Biotechnology; Cancer; Chemistry; Chemistry and Materials Science; Cholangiocarcinoma; Cholangiocarcinoma - genetics; Cholangiocarcinoma - pathology; Chromosome 3; Endoplasmic reticulum; Female; Gene expression; Gene Expression Regulation, Neoplastic; Gene regulation; Gene Regulatory Networks; Gene set enrichment analysis; Genes; genome; Genomic analysis; hazard ratio; Humans; Male; microRNA; MicroRNAs; MicroRNAs - genetics; miRNA; Original Article; patients; Prognosis; Protein folding; Therapeutic targets; therapeutics; uncertainty; Western blotting; Prognostic and diagnostic markers; MiR-26b-3p; Functional enrichment analysis; LncRNAs-miR-26b-3p-mRNAs network; Cholangiocarcinoma

MicroRNAs (miRNAs) reportedly play significant roles in the progression of various cancers and hold huge potential as both diagnostic tools and therapeutic targets. Given the ongoing uncertainty surrounding the precise functions of several miRNAs in cholangiocarcinoma (CCA), this research undertakes...