The therapeutic effectiveness of ibuprofen on the symptoms of naturally acquired common colds

• Published in: American journal of rhinology Vol. 15; no. 4; pp. 239 - 242
• Main Authors: Winther, B, Mygind, N
• Format: Journal Article
• Language: English
• Published: United States SAGE PUBLICATIONS, INC 01.07.2001
• Subjects: Adult; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Common Cold - classification; Common Cold - drug therapy; Double-Blind Method; Female; Humans; Ibuprofen - adverse effects; Ibuprofen - therapeutic use; Male; Middle Aged; Severity of Illness Index; Sneezing - drug effects

The pathogenesis of the common cold is associated with inflammation of the nasal mucous membrane with polymorphonuclear cells (PMNs)(1,2) and increased levels of inflammatory cytokines and mediators in nasal secretions.(3,4) We have investigated the effect of a nonsteroidal anti-inflammatory drug (N...