Transplantation of human menstrual blood progenitor cells improves hyperglycemia by promoting endogenous progenitor differentiation in type 1 diabetic mice

• Published in: Stem cells and development Vol. 23; no. 11; p. 1245
• Main Authors: Wu, Xiaoxing, Luo, Yueqiu, Chen, Jinyang, Pan, Ruolang, Xiang, Bingyu, Du, Xiaochun, Xiang, Lixin, Shao, Jianzhong, Xiang, Charlie
• Format: Journal Article
• Language: English
• Published: United States 01.06.2014
• Subjects: Animals; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental - blood; Diabetes Mellitus, Experimental - complications; Diabetes Mellitus, Experimental - therapy; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - therapy; Female; Hematopoiesis - physiology; Hematopoietic Stem Cells - cytology; Hematopoietic Stem Cells - physiology; Humans; Hyperglycemia - complications; Hyperglycemia - therapy; Male; Menstruation - blood; Mice; Mice, Inbred BALB C; Peripheral Blood Stem Cell Transplantation

Recently, a unique population of progenitor cells was isolated from human menstrual blood. The human menstrual blood progenitor cells (MBPCs) possess many advantages, such as the noninvasive acquisition procedure, broad multipotency, a higher proliferative rate, and low immunogenicity, and have attr...