A Randomized Study of Lung Cancer Screening with Spiral Computed Tomography: Three-year Results from the DANTE Trial

• Published in: American journal of respiratory and critical care medicine Vol. 180; no. 5; pp. 445 - 453
• Main Authors: Infante, Maurizio, Cavuto, Silvio, Lutman, Fabio Romano, Brambilla, Giorgio, Chiesa, Giuseppe, Ceresoli, Giovanni, Passera, Eliseo, Angeli, Enzo, Chiarenza, Maurizio, Aranzulla, Giuseppe, Cariboni, Umberto, Errico, Valentina, Inzirillo, Francesco, Bottoni, Edoardo, Voulaz, Emanuele, Alloisio, Marco, Destro, Anna, Roncalli, Massimo, Santoro, Armando, Ravasi, Gianluigi, DANTE Study Group
• Format: Journal Article
• Language: English
• Published: New York, NY Am Thoracic Soc 01.09.2009; American Thoracic Society
• Subjects: Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Cause of Death; Clinical death. Palliative care. Organ gift and preservation; Follow-Up Studies; Humans; Intensive care medicine; Italy - epidemiology; Lung cancer; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - mortality; Male; Mass Screening - methods; Medical sciences; Middle Aged; Prospective Studies; Radiography, Thoracic; Survival Rate; Tomography, Spiral Computed; Lung disease; Intensive care; screening; lung neoplasms; Respiratory disease; Lung cancer; Helical computed tomography; spiral computed tomography; Malignant tumor; Medical screening; randomized controlled trial; early diagnosis; Bronchus disease; Diagnosis; Resuscitation; Cancer

Screening for lung cancer with modern imaging technology may decrease lung cancer mortality, but encouraging results have only been obtained in uncontrolled studies. To explore the effect of screening with low-dose spiral computed tomography (LDCT) on lung cancer mortality. Secondary endpoints are i...