Age-related Changes in Bone Marrow Mesenchymal Stromal Cells A Potential Impact on Osteoporosis and Osteoarthritis Development

• Published in: Cell transplantation Vol. 26; no. 9; pp. 1520 - 1529
• Main Authors: Ganguly, Payal, El-Jawhari, Jehan J., Giannoudis, Peter V., Burska, Agata N., Ponchel, Frederique, Jones, Elena A.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.09.2017
• Subjects: Original; mesenchymal stromal cells (MSCs); in vivo; aging; bone marrow (BM); in vitro

Aging at the cellular level is a complex process resulting from accumulation of various damages leading to functional impairment and a reduced quality of life at the level of the organism. With a rise in the elderly population, the worldwide incidence of osteoporosis (OP) and osteoarthritis (OA) has...