LC-MS/MS platform-based serum untargeted screening reveals the diagnostic biomarker panel and molecular mechanism of breast cancer - Gong, Sisi; Wang, Qingshui; Huang, Jiewei; Huang, Rongfu; Chen, Shanshan; Cheng, Xiaojuan; Liu, Lei; Dai, Xiaofang; Zhong, Yameng; Fan, Chunmei; Liao, Zhijun (Methods (San Diego, Calif.), 2024)
Keywords: Biomarker; Biomarkers; Biomarkers, Tumor; blood serum; Breast cancer; breast neoplasms; Chromatography, Liquid - methods; Early Detection of Cancer; Female; Humans; Liquid Chromatography-Mass Spectrometry; Machine learning; mass spectrometry; metabolic diseases; metabolites; Metabolomics; Metabolomics - methods; pipecolic acid; regression analysis; Tandem Mass Spectrometry; Triple Negative Breast Neoplasms - diagnosis; Triple-negative breast cancer; ultra-performance liquid chromatography; NAT; Metabolomics; BC; Biomarker; Triple-negative breast cancer; AUC; TNM; QC; RSDs; CA15-3; ESI; TNBC; CEA; ML; AA; TCA cycle; OPLS-DA; ROC; UHPLC-MS; 7-MG; Breast cancer; PCA; BPC; 2-AG; Machine learning; HC; VIP; FC