Bioinformatics analysis of genes associated with the patchy-type alopecia areata: CD2 may be a new therapeutic target

• Published in: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia Vol. 164; no. 4; pp. 380 - 386
• Main Authors: Shi, Jiaxiao, Peng, Peng, Liu, Weixiao, Mi, Peng, Xing, Cong, Ning, Guangzhi, Feng, Shiqing
• Format: Journal Article
• Language: English
• Published: Czech Republic Palacký University Olomouc, Faculty of Medicine and Dentistry 01.12.2020
• Subjects: cd2; differentially expressed genes; function enrichment; patchy-type alopecia areata; protein‑protein interaction network; CD2; differentially expressed genes; function enrichment; patchy-type alopecia areata; protein‑protein interaction network

Alopecia areata (AA) is mainly a T cell-medicated autoimmune disease with non-scarring hair loss and limited treatment options. Of these, the patchy-type alopecia areata (AAP) is the most common and relatively easy to treat due to smaller areas of the scalp affected. To understand the pathogenesis o...