Salivary gland function 5 years after radioactive iodine ablation in patients with differentiated thyroid cancer: direct comparison of pre- and postablation scintigraphies and their relation to xerostomia symptoms

• Published in: Thyroid (New York, N.Y.) Vol. 23; no. 5; p. 609
• Main Authors: Jeong, Shin Young, Kim, Hae Won, Lee, Sang-Woo, Ahn, Byeong-Cheol, Lee, Jaetae
• Format: Journal Article
• Language: English
• Published: United States 01.05.2013
• Subjects: Adult; Aged; Combined Modality Therapy - adverse effects; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Humans; Iodine Radioisotopes - administration & dosage; Iodine Radioisotopes - adverse effects; Iodine Radioisotopes - therapeutic use; Male; Middle Aged; Prevalence; Radionuclide Imaging; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - adverse effects; Radiopharmaceuticals - therapeutic use; Republic of Korea - epidemiology; Salivary Glands - diagnostic imaging; Salivary Glands - physiopathology; Salivary Glands - radiation effects; Salivary Glands - secretion; Severity of Illness Index; Sialadenitis - diagnostic imaging; Sialadenitis - epidemiology; Sialadenitis - etiology; Sialadenitis - physiopathology; Submandibular Gland - diagnostic imaging; Submandibular Gland - physiopathology; Submandibular Gland - radiation effects; Submandibular Gland - secretion; Submandibular Gland Diseases - diagnostic imaging; Submandibular Gland Diseases - epidemiology; Submandibular Gland Diseases - etiology; Submandibular Gland Diseases - physiopathology; Thyroid Neoplasms - physiopathology; Thyroid Neoplasms - radiotherapy; Thyroid Neoplasms - surgery; Thyroidectomy; Xerostomia - diagnostic imaging; Xerostomia - epidemiology; Xerostomia - etiology; Xerostomia - physiopathology; Young Adult

Chronic sialadenitis is one of the most frequent chronic complications after radioactive iodine (RAI) therapy for thyroid cancer. To evaluate the long-term effects of RAI ablation on salivary gland function, we investigated scintigraphic changes in salivary glands by direct comparison of two salivar...